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[The advances of clinical and molecular prognostic factors of diffuse large B-cell lymphoma].

作者信息

Wang S N, Bai O

出版信息

Zhonghua Xue Ye Xue Za Zhi. 2016 Jun 14;37(6):538-41. doi: 10.3760/cma.j.issn.0253-2727.2016.06.022.

Abstract
摘要

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[Advances of aberrant signaling pathways and related targeting drugs in B cell non- Hodgkin lymphoma].
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FOXO1 activation is an effector of SYK and AKT inhibition in tonic BCR signal-dependent diffuse large B-cell lymphomas.
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A modified scoring of the NCCN-IPI is more accurate in the elderly and is improved by albumin and β2 -microglobulin.
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