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稳定磁场模拟咖啡因对神经元的作用。

Steady magnetic fields mimic the effect of caffeine on neurons.

作者信息

Azanza M J

机构信息

Departamento de Ciencias Morfológicas, Facultad de Medicina, Universidad de Zaragoza, Spain.

出版信息

Brain Res. 1989 Jun 5;489(1):195-8. doi: 10.1016/0006-8993(89)90025-5.

DOI:10.1016/0006-8993(89)90025-5
PMID:2743149
Abstract

We have observed that steady magnetic fields (SMF) of 1160 and 2600 gauss (G) mimic the inhibitory and excitatory actions of caffeine on neurons. We had observed that isolated mollusc neurons exposed to SMF were either inhibited or excited by mechanisms that appear Ca2+-dependent. Our results with caffeine corroborate that changes in Ca2+ kinetics underlie the electrophysiological membrane changes observed in neurons exposed to SMF.

摘要

我们观察到，1160高斯和2600高斯的稳恒磁场（SMF）模拟了咖啡因对神经元的抑制和兴奋作用。我们已经观察到，暴露于稳恒磁场的分离软体动物神经元，会通过似乎依赖钙离子的机制受到抑制或兴奋。我们使用咖啡因的研究结果证实，钙离子动力学的变化是暴露于稳恒磁场的神经元中观察到的电生理膜变化的基础。

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