Kamely Mohammad, Karimi Torshizi Mohammad Amir, Rahimi Shaban
Department of Poultry Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran, PO Box 14115-336.
Department of Poultry Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran, PO Box 14115-336
Poult Sci. 2016 Nov 1;95(11):2673-2678. doi: 10.3382/ps/pew227. Epub 2016 Jul 18.
Previously, we demonstrated that caffeine, a natural alkaloid, stimulates increased incidences of pulmonary hypertension syndrome (ascites) in broilers. The present study was designed to evaluate the ergogenic effects of caffeine on broiler performance and blood parameters. One-hundred-and-ninety-two Ross 308 male broiler chicks were randomly assigned at one d of age to 16 pens with 4 treatment groups. On d 3, the drinking water was supplemented with caffeine at levels of zero, 12.5, 25, and 50 mg/kg BW/day. Caffeine supplementation linearly improved (P < 0.01) body weight gain (BWG) and the feed conversion ratio (FCR); however, feed intake was not affected by caffeine (P > 0.05). On d 28, increasing caffeine supplementation caused linear reductions in plasma albumin, total protein, globulin, and triglyceride concentrations, and caffeine supplementation increased plasma uric acid concentrations (P < 0.05). On d 42, caffeine did not consistently affect plasma albumin, globulin, triglyceride, total protein, uric acid, or urea concentrations (P > 0.05), whereas plasma glucose concentrations increased linearly with increasing caffeine levels (P < 0.05). Plasma T concentrations were not affected by caffeine (P > 0.05), but plasma T concentrations were reduced by caffeine supplementation on d 28 and 42 (P < 0.05). The T:T ratios also were reduced by caffeine supplementation on d 42. Skin temperature was not influenced by caffeine supplementation (P > 0.05). There was a negative correlation between thyroid hormone concentrations and BW on d 42 (P < 0.05). It can be concluded that caffeine supplementation at the levels of 12.5 to 25 mg/kg BW/day increased BWG, decreased FCR and T, and significantly altered blood biochemistry parameters.
此前，我们证明了咖啡因这种天然生物碱会刺激肉鸡肺动脉高压综合征（腹水）发病率增加。本研究旨在评估咖啡因对肉鸡生产性能和血液参数的促力作用。192只罗斯308雄性肉雏鸡在1日龄时被随机分配到16个栏舍，分为4个处理组。在第3天，分别在饮用水中添加0、12.5、25和50mg/kg体重/天的咖啡因。添加咖啡因使体重增加（BWG）和饲料转化率（FCR）呈线性改善（P<0.01）；然而，采食量不受咖啡因影响（P>0.05）。在第28天，增加咖啡因添加量会使血浆白蛋白、总蛋白、球蛋白和甘油三酯浓度呈线性降低，且添加咖啡因会增加血浆尿酸浓度（P<0.05）。在第42天，咖啡因对血浆白蛋白、球蛋白、甘油三酯、总蛋白、尿酸或尿素浓度没有持续影响（P>0.05），而血浆葡萄糖浓度随咖啡因水平增加呈线性升高（P<0.05）。血浆睾酮（T）浓度不受咖啡因影响（P>0.05），但在第28天和第42天添加咖啡因会使血浆T浓度降低（P<0.05）。在第42天添加咖啡因也会降低T:T比值。皮肤温度不受添加咖啡因影响（P>0.05）。在第42天，甲状腺激素浓度与体重之间存在负相关（P<0.05）。可以得出结论，每天以12.5至25mg/kg体重的水平添加咖啡因可增加体重增加、降低饲料转化率和睾酮水平，并显著改变血液生化参数。
