Casolo G C, Buonafede N, Bertini G, Gensini G F, Petacchi D, Bartolozzi C
Cardiologia. 1989 Mar;34(3):229-36.
In order to evaluate the ability of magnetic resonance imaging (MRI) to detect acute myocardial infarction (AMI) in man, we studied 15 normal volunteers and 22 patients with a recent AMI (13.5 +/- 7.7 days, range 4-28). To establish the ability of MRI in localizing the site of infarction we also performed a comparison between the segments of the left ventricle showing evidence of AMI by MRI and those presenting wall motion abnormalities by 2-dimensional echocardiography. By using strict criteria and 2 imaging planes MRI proved to be a reliable technique for the detection of AMI. MRI correctly identified AMI in 20 out of 22 subjects (90.9%). The site of AMI appeared as an area of increased signal intensity on spin echo images, particularly evident on late echoes: 15 patients had MRI findings compatible with transmural AMI and 5 patients with non-transmural AMI. The site of AMI as detected by MRI closely correlated with that indicated by 2-dimensional echocardiography, thus showing that MRI is a reliable tool for AMI localization. We also observed that the number of left ventricular segments judged as infarcted by MRI was significantly higher than that showing wall motion abnormalities. As MRI correctly identified the presence of 2 subendocardial lesions, not detected by echocardiography, it is suggested that MRI may be superior to echocardiography in detecting non-transmural lesions and the lateral extension of a transmural infarct. Our data show that MRI is a reliable tool for the detection and location of recent AMI in man. In particular MRI can locate AMI with a precision similar to that offered by 2-dimensional echocardiography.
为了评估磁共振成像(MRI)检测人类急性心肌梗死(AMI)的能力,我们研究了15名正常志愿者和22例近期发生AMI的患者(13.5±7.7天,范围4 - 28天)。为了确定MRI定位梗死部位的能力,我们还对通过MRI显示有AMI证据的左心室节段与通过二维超声心动图显示有室壁运动异常的节段进行了比较。通过使用严格的标准和两个成像平面,MRI被证明是检测AMI的可靠技术。MRI在22名受试者中的20名(90.9%)中正确识别出AMI。在自旋回波图像上,AMI部位表现为信号强度增加的区域,在晚期回波上尤为明显:15例患者的MRI表现符合透壁性AMI,5例患者为非透壁性AMI。MRI检测到的AMI部位与二维超声心动图所示部位密切相关,因此表明MRI是用于AMI定位的可靠工具。我们还观察到,被MRI判定为梗死的左心室节段数量明显高于显示有室壁运动异常的节段数量。由于MRI正确识别出了2个二维超声心动图未检测到的心内膜下病变,提示在检测非透壁性病变和透壁性梗死的外侧扩展方面,MRI可能优于二维超声心动图。我们的数据表明,MRI是检测和定位人类近期AMI的可靠工具。特别是MRI能够以与二维超声心动图相似的精度定位AMI。