Kocvara R, Ptácek V, Tuíková J, Louzenský G, Koblízková L
Cas Lek Cesk. 1989 Feb 24;128(9):266-9.
Urolithiasis is a frequent disease greatly susceptible to recurrence. The concrements are most frequently caused by metabolical disorders. Metaphylaxis is a comprehensive and long-term regimen which should reduce the rate of recurrence. Non-specific metaphylaxis comprises a general liquid-taking and dietary regimen, specific metaphylaxis is based on the results of metabolical examination and concrement analysis. The authors present the results of comprehensive metaphylaxis in 124 patients (104 with calcium lithiasis and 22 with uric acid lithiasis). The concrement formation decreased from 1.13 of concrement per year prior to treatment, to 0.11 of concrement p. a. during treatment. After almost 5-years of follow-up and treatment, 77% patients had no recurrence, while in 94% it was substantially reduced. Metaphylaxis had no effect in 7 patients (6%). The uric-acid group showed better results than the calcium lithiasis group. The findings are comparable with literary data.
尿石症是一种易复发的常见疾病。结石形成最常见的原因是代谢紊乱。预防复发是一种全面且长期的治疗方案,旨在降低复发率。非特异性预防措施包括一般的液体摄入和饮食方案,特异性预防则基于代谢检查和结石分析的结果。作者展示了对124例患者(104例钙结石患者和22例尿酸结石患者)进行全面预防治疗的结果。结石形成从治疗前每年1.13例降至治疗期间每年0.11例。经过近5年的随访和治疗,77%的患者未复发,94%的患者复发率大幅降低。7例患者(6%)预防治疗无效。尿酸结石组的效果优于钙结石组。这些结果与文献数据相当。