Giordani Matteo, Mattioli Michele, Dogan Meral, Dogan Ahmet Umran
a Department of Pure and Applied Sciences , University of Urbino Carlo Bo , Urbino , Italy.
b Geological Engineering Department , Hacettepe University , Beytepe , Ankara , Turkey.
J Toxicol Environ Health A. 2016;79(18):808-24. doi: 10.1080/15287394.2016.1182453. Epub 2016 Jul 19.
Exposure of humans to erionite fibers of suitable morphology and dimension has been unambiguously linked to the occurrence of malignant mesothelioma. For this reason, a morphological, morphometrical, mineralogical, and chemical investigation was performed on two representative samples of potential carcinogenic, fibrous erionite from Lessini Mounts, northeastern (NE) Italy, which has not apparently been examined previously. The first sample is erionite-Ca with an extremely fibrous, hair-like and flexible appearance, and growth in intimate association with levyne. The second sample is erionite-Ca with prismatic to acicular crystals and rigid behavior, enriched in K(+) and Ca(2+) extra-framework cations. Although erionite is a nominally Fe-free phase, iron (Fe) was detected in low amounts in all the analyzed crystals. In both the investigated samples, erionite is present as individual fibers of respirable size. Considering that the toxicity and carcinogenic potential of erionite is associated with its size parameters, together with its in vivo durability and high surface area, most of the investigated fibers may also be potentially carcinogenic. The presence of erionite in extensively quarried and largely employed volcanic rocks, suggesting the need for detailed health-based studies in the region.
人类接触到具有合适形态和尺寸的毛沸石纤维已被明确地与恶性间皮瘤的发生联系起来。因此，对来自意大利东北部（NE）莱希尼山的两种具有潜在致癌性的纤维状毛沸石代表性样品进行了形态学、形态计量学、矿物学和化学研究，此前该地区显然未被研究过。第一个样品是毛沸石 - 钙，具有极其纤维状、毛发状且柔韧的外观，与歪晶共生生长。第二个样品也是毛沸石 - 钙，具有棱柱形至针状晶体且质地坚硬，富含钾（K⁺）和钙（Ca²⁺）等骨架外阳离子。尽管毛沸石名义上是无铁相，但在所有分析的晶体中都检测到了少量的铁（Fe）。在两个被研究的样品中，毛沸石均以可吸入尺寸的单根纤维形式存在。考虑到毛沸石的毒性和致癌潜力与其尺寸参数、体内耐久性和高表面积有关，大多数被研究的纤维也可能具有潜在致癌性。在广泛开采和大量使用的火山岩中存在毛沸石，这表明该地区需要进行基于健康的详细研究。
