Bubel Adam, Rogoziński Paweł, Bruliński Krzysztof
Pneumonol Alergol Pol. 2016;84(4):222-4. doi: 10.5603/PiAP.2016.0027.
A mature teratoma is a tumour of primary germ cells. It is often found in the mediastinum. The authors describe a case of a young man who demonstrated haemoptysis as the only symptom of a mediastinal tumour. The tumour was removed operatively, sent for histopathological examination and immunohistochemistry. The removed tumour was a mature teratoma including elements of the pancreas. The authors revealed the presence of trypsin in the pancreatic acinar cells. The proteolytic activity of the tumour was taken as the cause of haemoptysis because of enzymatic erosion of lung tissue intimately attached to the tumour. In such cases surgical removal saves life of patients.
成熟畸胎瘤是一种原发性生殖细胞肿瘤。它常发生于纵隔。作者描述了一例年轻男性病例,该患者以咯血作为纵隔肿瘤的唯一症状。肿瘤通过手术切除,送去做组织病理学检查和免疫组化。切除的肿瘤是一个包含胰腺成分的成熟畸胎瘤。作者发现胰腺腺泡细胞中存在胰蛋白酶。由于与肿瘤紧密相连的肺组织受到酶的侵蚀,肿瘤的蛋白水解活性被认为是咯血的原因。在这种情况下,手术切除可挽救患者生命。