Hu Kejia, Zhang Tiansong, Hutter Matthew, Xu Wendong, Williams Ziv
Department of Hand Surgery, Huashan Hospital, Fudan University, Shanghai, China; Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Department of Traditional Chinese Medicine, Jingan District Central Hospital, Fudan University, Shanghai, China.
World Neurosurg. 2016 Oct;94:409-417. doi: 10.1016/j.wneu.2016.07.023. Epub 2016 Jul 17.
Because peripheral nerve surgery has become more common in recent years, the pressure to increase this procedure's health care safety and cost-effectiveness has increased. Given our limited understanding, we evaluated prospectively identified and randomly sampled patients who underwent peripheral nerve surgery from 2005 to 2014 through the American College of Surgeons National Surgical Quality Improvement Program database.
We used bivariate testing and multivariate logistic regression analysis to identify patient- and surgery-related risk factors for postoperative complications and unplanned readmission in peripheral nerve surgery patients, and especially to estimate the impact of the nerve grafting procedure.
Overall, 2351 patients underwent peripheral nerve surgery, 120 complications were identified in 100 patients (4.25%), and 103 patients (4.38%) received nerve grafting. Thirty-one of the 1593 patients (1.95%) underwent unplanned readmission. Nerve grafting procedures had no association with postoperative complications and unplanned readmission rates. Patients who experienced an inpatient procedure (odds ratio [OR], 2.54; P < 0.001), a longer operative time (OR, 1.00; P < 0.001), and worse wound classifications (OR, 1.83; P < 0.001) all had increased odds of postoperative complications. An inpatient procedure (OR, 2.74; P = 0.014) and any complications (OR, 24.43; P < 0.001) were significantly associated with unplanned readmission.
Our study confirms that peripheral nerve surgery and nerve graft procedures can be safely performed with low complication risks and low unplanned readmission rates. We also identified the risks associated with perioperative adverse outcomes, and these data may be used as an adjunct for risk stratification for patients under consideration for peripheral nerve surgery. This approach may enable the improved targeting of the most costly and harmful complications of preventive measures.
近年来,由于周围神经手术变得更加常见,提高该手术医疗安全性和成本效益的压力也随之增加。鉴于我们的了解有限,我们通过美国外科医师学会国家外科质量改进计划数据库,对2005年至2014年期间接受周围神经手术的前瞻性识别和随机抽样患者进行了评估。
我们使用双变量检验和多变量逻辑回归分析,以确定周围神经手术患者术后并发症和非计划再入院的患者及手术相关风险因素,尤其要评估神经移植手术的影响。
总体而言,2351例患者接受了周围神经手术,100例患者(4.25%)出现120例并发症,103例患者(4.38%)接受了神经移植。1593例患者中有31例(1.95%)接受了非计划再入院。神经移植手术与术后并发症和非计划再入院率无关。经历住院手术的患者(比值比[OR],2.54;P<0.001)、手术时间较长的患者(OR,1.00;P<0.001)以及伤口分类较差的患者(OR,1.83;P<0.001)术后并发症的几率均增加。住院手术(OR,2.74;P=0.014)和任何并发症(OR,24.43;P<0.001)与非计划再入院显著相关。
我们的研究证实,周围神经手术和神经移植手术可以安全地进行,并发症风险低,非计划再入院率低。我们还确定了围手术期不良结局相关风险,这些数据可作为考虑进行周围神经手术患者风险分层的辅助手段。这种方法可能有助于更好地针对预防措施中最昂贵和最有害的并发症。