轻链多发性骨髓瘤中的淀粉样变性神经病
Amyloid neuropathy in light chain multiple myeloma.
作者信息
Schenone A, Primavera A, De Martini I, Bianchini D, Mancardi G L
机构信息
Institute of Clinical Neurology, University of Genoa, Italy.
出版信息
Clin Neuropathol. 1989 May-Jun;8(3):156-7.
PMID:2743653
Abstract
We describe a 73-year-old man with peripheral neuropathy and light chain lambda-type myeloma. A sural nerve biopsy showed the typical neuropathological picture of amyloid neuropathy. With the present case we first demonstrate amyloid deposits in peripheral nerves during light chain multiple myeloma and stress the importance of amyloidosis in the development of peripheral neuropathy.
摘要
我们描述了一名患有周围神经病变和λ型轻链骨髓瘤的73岁男性。腓肠神经活检显示出淀粉样变性周围神经病的典型神经病理学表现。通过本病例，我们首次证实了轻链多发性骨髓瘤患者周围神经中存在淀粉样沉积物，并强调了淀粉样变性在周围神经病变发生过程中的重要性。
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