Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
EuroIntervention. 2016 Jul 20;12(4):456-64. doi: 10.4244/EIJV12I4A79.
Non-compliant balloons provide uniform radial force along the vessel wall at any inflation pressure. As a result, the use of non-compliant balloons may reduce side branch complications and optimise stent deployment. We sought to investigate the impact of non-compliant balloons on the long-term clinical outcomes of patients undergoing a coronary bifurcation intervention.
A total of 2,897 patients treated with drug-eluting stents for bifurcation lesions were enrolled. Non-compliant balloons were used in 752 patients (26%). During a median three-year follow-up, major adverse cardiac events (MACE: cardiac death, myocardial infarction, or target lesion revascularisation) occurred less frequently in the non-compliant balloon group than in the compliant balloon group (8.2% versus 10.9%; p=0.03). After propensity score matching (710 pairs), the use of non-compliant balloons resulted in a lower rate of side branch dissection (0.1% versus 1.1%; p=0.046) and a higher rate of procedural success (79.0% versus 73.9%; p=0.01). The use of non-compliant balloons was associated with a lower risk of MACE (HR 0.64, 95% CI: 0.46-0.91; p=0.01) and cardiac death (HR 0.14, 95% CI: 0.03-0.64; p=0.01).
The use of non-compliant balloons was associated with favourable procedural and long-term clinical outcomes in patients receiving coronary bifurcation intervention.
顺应性球囊在任何充气压力下都能沿血管壁提供均匀的径向力。因此，使用顺应性球囊可能会减少侧支并发症并优化支架扩张。我们旨在研究顺应性球囊对接受冠状动脉分叉介入治疗的患者长期临床结局的影响。
共纳入 2897 例接受药物洗脱支架治疗的分叉病变患者。在 752 例患者（26%）中使用了顺应性球囊。在中位三年随访期间，顺应性球囊组的主要不良心脏事件（MACE：心脏死亡、心肌梗死或靶病变血运重建）发生率低于非顺应性球囊组（8.2%比 10.9%；p=0.03）。经过倾向评分匹配（710 对）后，非顺应性球囊组的侧支血管夹层发生率较低（0.1%比 1.1%；p=0.046），手术成功率较高（79.0%比 73.9%；p=0.01）。使用非顺应性球囊与较低的 MACE 风险相关（HR 0.64，95%CI：0.46-0.91；p=0.01）和心脏死亡风险相关（HR 0.14，95%CI：0.03-0.64；p=0.01）。
在接受冠状动脉分叉介入治疗的患者中，使用非顺应性球囊与有利的手术和长期临床结局相关。
