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斯图尔特法在评估血气参数中的有效性。

Effectiveness of the Stewart Method in the Evaluation of Blood Gas Parameters.

作者信息

Gezer Mustafa, Bulucu Fatih, Ozturk Kadir, Kilic Selim, Kaldirim Umit, Eyi Yusuf Emrah

机构信息

Department of Internal Medicine, Mevki Military Hospital, Ankara, Turkey.

Department of Internal Medicine, Gulhane Military Medical Academy, Ankara, Turkey.

出版信息

Turk J Emerg Med. 2016 Mar 2;15(1):3-7. doi: 10.5505/1304.7361.2014.73604. eCollection 2015 Mar.

DOI:10.5505/1304.7361.2014.73604
PMID:27437520
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4909963/
Abstract

OBJECTIVES

In 1981, Peter A. Stewart published a paper describing his concept for employing Strong Ion Difference. In this study we compared the HCO3 levels and Anion Gap (AG) calculated using the classic method and the Stewart method.

METHODS

Four hundred nine (409) arterial blood gases of 90 patients were collected retrospectively. Some were obtained from the same patients in different times and conditions. All blood samples were evaluated using the same device (ABL 800 Blood Gas Analyzer). HCO3 level and AG were calculated using the Stewart method via the website AcidBase.org. HCO3 levels, AG and strong ion difference (SID) were calculated using the Stewart method, incorporating the parameters of age, serum lactate, glucose, sodium, and pH, etc.

RESULTS

According to classic method, the levels of HCO3 and AG were 22.4±7.2 mEq/L and 20.1±4.1 mEq/L respectively. According to Stewart method, the levels of HCO3 and AG were 22.6±7.4 and 19.9±4.5 mEq/L respectively.

CONCLUSIONS

There was strong correlation between the classic method and the Stewart method for calculating HCO3 and AG. The Stewart method may be more effective in the evaluation of complex metabolic acidosis.

摘要

目的

1981年,彼得·A·斯图尔特发表了一篇论文,阐述了他运用强离子差的概念。在本研究中,我们比较了使用经典方法和斯图尔特方法计算的HCO3水平和阴离子间隙(AG)。

方法

回顾性收集了90例患者的409份动脉血气样本。其中一些样本来自同一患者在不同时间和条件下。所有血样均使用同一设备(ABL 800血气分析仪)进行评估。通过AcidBase.org网站使用斯图尔特方法计算HCO3水平和AG。使用斯图尔特方法,结合年龄、血清乳酸、葡萄糖、钠和pH等参数计算HCO3水平、AG和强离子差(SID)。

结果

根据经典方法,HCO3和AG水平分别为22.4±7.2 mEq/L和20.1±4.1 mEq/L。根据斯图尔特方法,HCO3和AG水平分别为22.6±7.4和19.9±4.5 mEq/L。

结论

经典方法与斯图尔特方法在计算HCO3和AG方面具有很强的相关性。斯图尔特方法在评估复杂代谢性酸中毒方面可能更有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3275/4909963/3077272a7824/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3275/4909963/3077272a7824/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3275/4909963/3077272a7824/gr1.jpg

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本文引用的文献

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Clin J Am Soc Nephrol. 2009 Jul;4(7):1267-74. doi: 10.2215/CJN.01820309. Epub 2009 Jun 11.
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Correction of the anion gap for albumin in order to detect occult tissue anions in shock.校正白蛋白的阴离子间隙以检测休克时隐匿的组织阴离子。
Arch Dis Child. 2002 Dec;87(6):526-9. doi: 10.1136/adc.87.6.526.
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Clinical assessment of acid-base status: comparison of the Henderson-Hasselbalch and strong ion approaches.
酸碱平衡状态的临床评估:亨德森-哈塞尔巴尔赫法与强离子方法的比较
Vet Clin Pathol. 2000;29(4):115-128. doi: 10.1111/j.1939-165x.2000.tb00241.x.
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Am J Respir Crit Care Med. 2000 Dec;162(6):2246-51. doi: 10.1164/ajrccm.162.6.9904099.
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Anaesth Intensive Care. 2000 Aug;28(4):399-402. doi: 10.1177/0310057X0002800407.
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Accuracy of base excess--an in vitro evaluation of the Van Slyke equation.
Crit Care Med. 2000 Aug;28(8):2932-6. doi: 10.1097/00003246-200008000-00041.
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Anion gap and hypoalbuminemia.阴离子间隙与低白蛋白血症。
Crit Care Med. 1998 Nov;26(11):1807-10. doi: 10.1097/00003246-199811000-00019.