Women's College Hospital, Toronto, ON, Canada.
University of Toronto, Toronto, ON, Canada.
Acta Psychiatr Scand. 2016 Oct;134(4):305-13. doi: 10.1111/acps.12622. Epub 2016 Jul 20.
We aimed to identify factors associated with postpartum psychiatric admission in schizophrenia.
In a population-based cohort study of 1433 mothers with schizophrenia in Ontario, Canada (2003-2011), we compared women with and without psychiatric admission in the 1st year postpartum on demographic, maternal medical/obstetrical, infant and psychiatric factors and identified factors independently associated with admission.
Admitted women (n = 275, 19%) were less likely to be adolescents, more likely to be low income and less likely to have received prenatal ultrasound before 20 weeks gestation compared to non-admitted women. They also had higher rates of predelivery psychiatric comorbidity and mental health service use. Factors independently associated with postpartum admission were age (<20 vs. ≥35 years: adjusted risk ratio, aRR, 0.48, 95% CI 0.24-0.96), income (lowest vs. highest income: aRR 1.67, 1.13-2.47) and the following mental health service use factors in pregnancy: admission (≥35 days/year vs. no days, aRR 4.54, 3.65-5.65), outpatient mental health care (no visits vs. ≥2 visits aRR 0.35, 0.27-0.47) and presence of a consistent mental health care provider during pregnancy (aRR 0.69, 0.54-0.89).
Certain subgroups of women with schizophrenia may benefit from targeted intervention to mitigate risk for postpartum admission.
我们旨在确定与精神分裂症产后精神病住院相关的因素。
在加拿大安大略省的一项基于人群的队列研究中,纳入了 1433 名患有精神分裂症的母亲(2003-2011 年),我们比较了产后第一年有和没有精神病住院的女性在人口统计学、产妇医疗/产科、婴儿和精神科因素方面的差异,并确定了与住院相关的独立因素。
与未住院的女性相比,住院女性(n=275,19%)更年轻,更可能收入较低,在 20 周妊娠前接受产前超声检查的可能性较小。她们也有更高的产前精神共病和精神卫生服务使用率。与产后住院相关的独立因素是年龄(<20 岁与≥35 岁:调整后的风险比 aRR,0.48,95%可信区间 0.24-0.96)、收入(最低与最高收入:aRR 1.67,1.13-2.47)和怀孕期间以下精神卫生服务使用因素:住院(≥35 天/年与无住院天数:aRR 4.54,3.65-5.65)、门诊精神卫生保健(无就诊与≥2 次就诊 aRR 0.35,0.27-0.47)和怀孕期间有稳定的精神卫生保健提供者(aRR 0.69,0.54-0.89)。
某些特定亚组的精神分裂症女性可能需要针对性的干预,以降低产后住院的风险。