台湾南部 12 年经验显示：肺炎克雷伯菌感染导致内源性眼内炎的预后不良。
Klebsiella pneumoniae Infection Leads to a Poor Visual Outcome in Endogenous Endophthalmitis: A 12-year Experience in Southern Taiwan.
机构信息
a Department of Ophthalmology , Kaohsiung Veterans General Hospital , Kaohsiung , Taiwan.
b Program of Health-Business Administration , Fooyin University , Kaohsiung , Taiwan.
出版信息
Ocul Immunol Inflamm. 2017 Dec;25(6):870-877. doi: 10.1080/09273948.2016.1193616. Epub 2016 Jul 20.
PURPOSE
To compare the characteristics, visual outcome, and prognostic factors of patients with endogenous endophthalmitis and to determine the association of endophthalmitis with Klebsiella pneumoniae infection.
METHODS
We retrospectively analyzed records of patients diagnosed with endogenous endophthalmitis from January 2002 to August 2013.
RESULTS
A total of 86 patients were diagnosed with endogenous endophthalmitis; 48 patients were infected with K. pneumoniae, 28 patients were infected with other pathogens, and 10 were culture-negative. Diabetes mellitus was more prevalent among patients infected with K. pneumoniae. Liver abscess and urinary tract infection were the leading sources of infection in patients with and without a K. pneumoniae infection, respectively. In patients with endogenous endophthalmitis, poor initial vision (p<0.001) and K. pneumoniae infection (p = 0.048) were significantly associated with a poor visual outcome.
CONCLUSIONS
Poor initial vision and K. pneumoniae infection were significantly associated with poorer visual outcome for patients with endogenous endophthalmitis.
目的
比较内源性眼内炎患者的特征、视力结果和预后因素，并确定内眼炎与肺炎克雷伯菌感染之间的关系。
方法
我们回顾性分析了 2002 年 1 月至 2013 年 8 月期间诊断为内源性眼内炎的患者记录。
结果
共诊断出 86 例内源性眼内炎患者；48 例患者感染肺炎克雷伯菌，28 例患者感染其他病原体，10 例培养阴性。感染肺炎克雷伯菌的患者中糖尿病更为常见。肝脓肿和尿路感染分别是有和没有肺炎克雷伯菌感染患者的主要感染源。在内源性眼内炎患者中，初始视力较差（p<0.001）和肺炎克雷伯菌感染（p=0.048）与较差的视力结果显著相关。
结论
初始视力差和肺炎克雷伯菌感染与内源性眼内炎患者的视力预后较差显著相关。
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