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非体外循环冠状动脉旁路移植术同期冠状动脉内膜切除术治疗弥漫性冠状动脉疾病

[Off-pump Coronary Artery Bypass Grafting with Concomitant Coronary Endarterectomy for the Diffusely Diseased Coronary Artery].

作者信息

Nishigawa Kosaku, Takanashi Shuichiro

机构信息

Department of Cardiovascular Surgery, Sakakibara Heart Institute, Fuchu, Japan.

出版信息

Kyobu Geka. 2016 Jul;69(8):594-8.

Abstract

Recent progress in percutaneous coronary intervention has driven more patients with complex or diffuse coronary artery disease to be referred for surgical revascularization. Coronary endarterectomy (CE) is a treatment option for diffusely diseased coronary arteries. On the other hand, off-pump coronary artery bypass grafting (off-pump CABG) has currently been the standard procedure for surgical revascularization in patients with coronary artery disease. We performed off-pump CABG with concomitant CE for the diffusely diseased left anterior descending artery( LAD) for 194 patients from September 2004 to August 2015. Mean age was 66.5±8.9 years and 168 were male. Mean preoperative ejection fraction was 54.9±12.4%. Mean length of arteriotomy in the LAD was 6.1±1.9 cm and endarterectomized LAD was reconstructed using the internal thoracic artery (ITA) with an onlay-patch fashion in all patients. On-pump conversion was required in 13( 6.7%) patients. 17( 8.8%) patients suffered from perioperative myocardial infarction. The 30-day mortality was 1.0 %.Patency rate of the reconstructed LAD at early postoperative angiography was 93.3%( 181/194). In summary, CE with onlay-patch grafting using the ITA for the diffusely diseased LAD with an off-pump technique can be performed safely with satisfactory outcomes.

摘要

经皮冠状动脉介入治疗的最新进展促使更多患有复杂或弥漫性冠状动脉疾病的患者被转诊接受外科血运重建治疗。冠状动脉内膜切除术(CE)是弥漫性冠状动脉疾病的一种治疗选择。另一方面,非体外循环冠状动脉旁路移植术(非体外循环CABG)目前已成为冠状动脉疾病患者外科血运重建的标准手术。2004年9月至2015年8月,我们对194例弥漫性病变的左前降支动脉(LAD)患者进行了非体外循环CABG并同期行CE。平均年龄为66.5±8.9岁,男性168例。术前平均射血分数为54.9±12.4%。LAD的平均动脉切开长度为6.1±1.9 cm,所有患者均采用内乳动脉(ITA)以覆盖补片方式重建内膜切除后的LAD。13例(6.7%)患者需要转为体外循环。17例(8.8%)患者发生围手术期心肌梗死。30天死亡率为1.0%。术后早期血管造影显示重建LAD的通畅率为93.3%(181/194)。总之,采用非体外循环技术,对弥漫性病变的LAD行ITA覆盖补片移植同期CE可安全进行,效果满意。

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