Gola Mateusz, Potenza Marc N
1 Swartz Center for Computational Neuroscience, Institute for Neural Computations, University of California San Diego , San Diego, CA, USA.
2 Institute of Psychology, Polish Academy of Sciences , Warsaw, Poland.
J Behav Addict. 2016 Sep;5(3):529-32. doi: 10.1556/2006.5.2016.046. Epub 2016 Jul 21.
Background How best to conceptualize problematic pornography use (PPU) and intervene most effectively remain debated, with obsessive-compulsive disorder (OCD) and addiction frameworks. We investigated the efficacy of the serotonin-reuptake inhibitor paroxetine in combination with cognitive-behavioral therapy in the treatment of problematic pornography use (PPU). Case presentation Three heterosexual males with PPU were treated with cognitive-behavioral therapy and paroxetine. Frequency of pornography use, other sexual behaviors, and anxiety were assessed during treatment. Discussion Paroxetine treatment, although seemingly initially effective in reducing pornography use and anxiety, appeared related to new compulsive sexual behaviors after 3 months. Conclusions Paroxetine may hold promise for short-term reduction of PPU and related anxiety, but new potentially distressing sexual behaviors may emerge. The cases suggest that PPU may arise from multiple domains. We propose an explanation of the effects based on recent neuroscientific research on sexual behaviors and alcohol use.
背景 如何最好地概念化问题性色情使用(PPU)并最有效地进行干预仍存在争议,存在强迫症(OCD)和成瘾框架。我们研究了5-羟色胺再摄取抑制剂帕罗西汀联合认知行为疗法治疗问题性色情使用(PPU)的疗效。病例报告 三名患有PPU的异性恋男性接受了认知行为疗法和帕罗西汀治疗。在治疗期间评估色情使用频率、其他性行为和焦虑情况。讨论 帕罗西汀治疗虽然最初似乎能有效减少色情使用和焦虑,但在3个月后似乎与新的强迫性性行为有关。结论 帕罗西汀可能有望在短期内减少PPU及相关焦虑,但可能会出现新的潜在令人苦恼的性行为。这些病例表明,PPU可能源于多个领域。我们基于近期关于性行为和酒精使用的神经科学研究对这些效应提出一种解释。