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基层医疗急救医院用药安全系统的比较:两项研究的综合分析

Comparison of medication safety systems in critical access hospitals: Combined analysis of two studies.

作者信息

Cochran Gary L, Barrett Ryan S, Horn Susan D

机构信息

Department of Pharmacy Practice, University of Nebraska Medical Center, Omaha, NE.

Institute for Clinical Outcomes Research, International Severity Information Systems, Salt Lake City, UT.

出版信息

Am J Health Syst Pharm. 2016 Aug 1;73(15):1167-73. doi: 10.2146/ajhp150760.

Abstract

PURPOSE

The role of pharmacist transcription, onsite pharmacist dispensing, use of automated dispensing cabinets (ADCs), nurse-nurse double checks, or barcode-assisted medication administration (BCMA) in reducing medication error rates in critical access hospitals (CAHs) was evaluated.

METHODS

Investigators used the practice-based evidence methodology to identify predictors of medication errors in 12 Nebraska CAHs. Detailed information about each medication administered was recorded through direct observation. Errors were identified by comparing the observed medication administered with the physician's order. Chi-square analysis and Fisher's exact test were used to measure differences between groups of medication-dispensing procedures.

RESULTS

Nurses observed 6497 medications being administered to 1374 patients. The overall error rate was 1.2%. The transcription error rates for orders transcribed by an onsite pharmacist were slightly lower than for orders transcribed by a telepharmacy service (0.10% and 0.33%, respectively). Fewer dispensing errors occurred when medications were dispensed by an onsite pharmacist versus any other method of medication acquisition (0.10% versus 0.44%, p = 0.0085). The rates of dispensing errors for medications that were retrieved from a single-cell ADC (0.19%), a multicell ADC (0.45%), or a drug closet or general supply (0.77%) did not differ significantly. BCMA was associated with a higher proportion of dispensing and administration errors intercepted before reaching the patient (66.7%) compared with either manual double checks (10%) or no BCMA or double check (30.4%) of the medication before administration (p = 0.0167).

CONCLUSION

Onsite pharmacist dispensing and BCMA were associated with fewer medication errors and are important components of a medication safety strategy in CAHs.

摘要

目的

评估药剂师转录、现场药剂师配药、使用自动配药柜(ADC)、护士双人核对或条形码辅助给药(BCMA)在降低基层医疗急救医院(CAH)用药错误率方面的作用。

方法

研究人员采用基于实践的证据方法,确定内布拉斯加州12家CAH中用药错误的预测因素。通过直接观察记录每种给药药物的详细信息。通过将观察到的给药药物与医生的医嘱进行比较来识别错误。采用卡方分析和Fisher精确检验来衡量不同配药程序组之间的差异。

结果

护士观察到向1374名患者给药6497次。总体错误率为1.2%。现场药剂师转录医嘱的错误率略低于远程药房服务转录的医嘱(分别为0.10%和0.33%)。与任何其他获取药物的方法相比,现场药剂师配药时发生的配药错误更少(0.10%对0.44%,p = 0.0085)。从单格ADC、多格ADC或药品柜或一般供应处获取的药物的配药错误率(分别为0.19%、0.45%和0.77%)没有显著差异。与给药前人工双人核对(10%)或不进行BCMA或双人核对(30.4%)相比,BCMA与在药物到达患者之前拦截的配药和给药错误比例更高(66.7%)相关(p = 0.0167)。

结论

现场药剂师配药和BCMA与较少的用药错误相关,是CAH用药安全策略的重要组成部分。

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