Ma Xinling, Chen Yuke, Huang Fangyan, Luo Qianying, Lv Hui, Long Hua
Nursing Department, Youjiang Medical University for Nationalities, Baise City, China. Email:
General Surgical Department, Affiliated hospital of Youjiang Medical University for Nationalities, Baise City, China.
Asia Pac J Clin Nutr. 2016;25(3):529-33. doi: 10.6133/apjcn.102015.04.
Food intolerance is believed to be a source of frequent medical problems in ulcerative colitis (UC), which closely correlate with patients' dietary pattern. Living in an underdeveloped area of China, residents in southwestern region have diverse dietary habits. The objective of this study is to determine the prevalence of food intolerance in the UC patients in this area and to discuss some of the possible risk factors leading to the condition.
Food antibodies in serum of 80 patients with active UC were determined by standard enzyme-linked immuno sorbent assay (ELISA). This study examined the risk factors contributing to high titers of food antibodies and the dietary patterns correlating with food intolerance in these demographics.
83.8% of patients (67/80) were found to be seropositive for food intolerance. Patients of female, aged between 20 to 40 and the one who tended to have a high fat diet were tested to be highly seropositive (p<0.05). Neither spicy food intake nor the course the disease manifested any relationship with the presence of food intolerance (p>0.05).
Active UC patients in southwestern region of China have showed to be high seropositive in food intolerance, particularly in female and young patients. Dietary patterns with high in fat intake seem to have caused high prevalence of seropositivity in food intolerance. Although rice has been taken as staple food and the spicy food has been popular among citizen in this region, these foods have indicated to no effect on food intolerance in this study.
食物不耐受被认为是溃疡性结肠炎（UC）中常见医学问题的一个来源，它与患者的饮食习惯密切相关。中国西南部地区属于欠发达地区，当地居民饮食习惯多样。本研究的目的是确定该地区UC患者中食物不耐受的患病率，并探讨一些可能导致这种情况的危险因素。
采用标准酶联免疫吸附测定（ELISA）法测定80例活动期UC患者血清中的食物抗体。本研究调查了导致食物抗体高滴度的危险因素以及这些人群中与食物不耐受相关的饮食习惯。
83.8%的患者（67/80）食物不耐受血清学检测呈阳性。女性患者、年龄在20至40岁之间且倾向于高脂肪饮食的患者血清学检测呈高度阳性（p<0.05）。辛辣食物摄入量和疾病病程与食物不耐受的存在均无关联（p>0.05）。
中国西南部地区的活动期UC患者食物不耐受血清学检测呈高度阳性，尤其是女性和年轻患者。高脂肪摄入的饮食习惯似乎导致了食物不耐受血清学阳性的高患病率。尽管大米是该地区的主食且辛辣食物很受欢迎，但在本研究中这些食物对食物不耐受并无影响。
