Touska Philip, Srikanthan Ahgi, Amarasinghe Kavita, Jawad Susan
Department of Radiology, St. George's Hospital NHS Trust, London, UK.
Department of Cellular Pathology, St. George's Hospital NHS Trust, London, UK.
BMJ Case Rep. 2016 Jul 20;2016:bcr2015213184. doi: 10.1136/bcr-2015-213184.
A 19-year-old patient presented with slowly enlarging, painless, left-sided cervical mass. She had a background of multiple endocrine neoplasia 2B and had undergone a total thyroidectomy for medullary thyroid carcinoma during childhood. A cervical recurrence was therefore suspected. Ultrasonographic and MRI examination revealed a well-defined lesion within the left sternocleidomastoid muscle. Further evaluation with sestamibi and single-photon emission CT revealed elevated tracer uptake within the lesion. Cytological analysis, following ultrasound-guided sampling, revealed absent staining for calcitonin and blood samples confirmed a normal serum calcitonin level; however, the serum parathyroid hormone level was elevated. Overall, summative findings were consistent with a diagnosis of a parathyroid adenoma arising within the left sternocleidomastoid muscle. Given that this is not a location for a physiological parathyroid tissue, the adenoma might have arisen within the autotransplanted parathyroid tissue, injected into the muscular sheath during thyroidectomy. The clinical, radiological and pathological features are considered in this article.
一名19岁患者出现左侧颈部肿物,肿物缓慢增大,无痛。她有多发性内分泌腺瘤病2B病史,童年时因甲状腺髓样癌接受了甲状腺全切术。因此怀疑有颈部复发。超声和MRI检查显示左侧胸锁乳突肌内有一个边界清晰的病变。用甲氧基异丁基异腈和单光子发射计算机断层扫描进一步评估显示病变内示踪剂摄取增加。超声引导下采样后的细胞学分析显示降钙素染色阴性,血液样本证实血清降钙素水平正常;然而,血清甲状旁腺激素水平升高。总体而言,总结性结果与左侧胸锁乳突肌内发生甲状旁腺腺瘤的诊断一致。鉴于此并非生理性甲状旁腺组织的位置,该腺瘤可能起源于甲状腺切除术中注入肌肉鞘内的自体移植甲状旁腺组织。本文对其临床、影像学和病理特征进行了探讨。