Zwisler Ann-Dorthe, Norton Rebecca J, Dean Sarah G, Dalal Hayes, Tang Lars H, Wingham Jenny, Taylor Rod S
Danish Centre of Rehabilitation and Palliative Care, University Hospital Odense, Odense, Denmark; University of Southern Denmark, Odense, Denmark.
Institute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, UK.
Int J Cardiol. 2016 Oct 15;221:963-9. doi: 10.1016/j.ijcard.2016.06.207. Epub 2016 Jun 28.
To assess the effectiveness of home-based cardiac rehabilitation (CR) for heart failure compared to either usual medical care (i.e. no CR) or centre-based CR on mortality, morbidity, exercise capacity, health-related quality of life, drop out, adherence rates, and costs.
Randomised controlled trials were initially identified from previous systematic reviews of CR. We undertook updated literature searches of MEDLINE, EMBASE, CINAHL, PsycINFO and Cochrane Library to December 2015. A total of 19 trials with median follow up of 3months were included - 17 comparisons of home-based CR to usual care (995 patients) and four comparing home and centre-based CR (295 patients).
Compared to usual care, home-based CR improved VO2max (mean difference: 1.6ml/kg/min, 0.8 to 2.4) and total Minnesota Living with Quality of Life score (-3.3, -7.5 to 1.0), with no difference in mortality, hospitalisation or study drop out. Outcomes and costs were similar between home-based and centre-based CR with the exception of higher levels of trial completion in the home-based group (relative risk: 1.2, 1.0 to 1.3).
Home-based CR results in short-term improvements in exercise capacity and health-related quality of life of heart failure patients compared to usual care. The magnitude of outcome improvement is similar to centre-based CR. Home-based CR appears to be safe with no evidence of increased risk of hospitalisation or death. These findings support the provision of home-based CR for heart failure as an evidence-based alternative to the traditional centre-based model of provision.
评估与常规医疗护理(即无心脏康复)或基于中心的心脏康复相比,家庭心脏康复(CR)对心力衰竭患者死亡率、发病率、运动能力、健康相关生活质量、退出率、依从率和成本的效果。
最初从之前关于心脏康复的系统评价中识别随机对照试验。我们对MEDLINE、EMBASE、CINAHL、PsycINFO和Cochrane图书馆进行了更新的文献检索,截至2015年12月。共纳入19项试验,中位随访时间为3个月——17项家庭心脏康复与常规护理的比较(995例患者)以及4项家庭和基于中心的心脏康复的比较(295例患者)。
与常规护理相比,家庭心脏康复改善了最大摄氧量(平均差异:1.6ml/kg/min,0.8至2.4)和明尼苏达生活质量总分(-3.3,-7.5至1.0),在死亡率、住院率或研究退出率方面无差异。家庭和基于中心的心脏康复在结果和成本方面相似,但家庭组的试验完成率较高(相对风险:1.2,1.0至1.3)。
与常规护理相比,家庭心脏康复可使心力衰竭患者的运动能力和健康相关生活质量在短期内得到改善。结果改善的幅度与基于中心的心脏康复相似。家庭心脏康复似乎是安全的,没有证据表明住院或死亡风险增加。这些发现支持为心力衰竭患者提供家庭心脏康复,作为传统基于中心的康复模式的循证替代方案。