Department of Neurology, 125 Paterson Street, Suite 6200, New Brunswick, NJ 08901, United States.
Cytokine. 2016 Oct;86:4-5. doi: 10.1016/j.cyto.2016.06.027. Epub 2016 Jul 18.
Inflammation is believed to be a component of a number of degenerative brain diseases including Alzheimer's disease. A recent article by Fu and colleagues (2016) demonstrated that the cytokine IL-33 can modulate microglia in an animal model of AD to become better scavengers of beta-amyloid and less pro-inflammatory. The findings have potential therapeutic implications for a number of brain conditions.
炎症被认为是包括阿尔茨海默病在内的一些退行性脑疾病的组成部分。最近，Fu 及其同事（2016）的一篇文章表明，细胞因子 IL-33 可以在 AD 动物模型中调节小胶质细胞，使其成为更好的β-淀粉样蛋白清除物，减少促炎作用。这些发现对许多脑部疾病具有潜在的治疗意义。
