RWTH Aachen University, Aachener Verfahrenstechnik, Chemical Process Engineering (CVT), Aachen, 52064, Germany.
Soft Matter. 2016 Aug 21;12(31):6512-7. doi: 10.1039/c6sm01345g. Epub 2016 Jul 22.
Understanding the separation, concentration and purification processes of soft nanoparticles is essential for numerous applications in water filtration, bioprocessing and blood separation. Here we report unique translocation and rejection features of sub-micron sized microgels during frontal filtration using membranes having micron-sized porosity. Simultaneously measuring the increase in hydraulic resistance and electrical impedance change allows us to clearly distinguish two deposition phases: (a) microgel accumulation within the depth of the membrane porosity and (b) subsequent formation of a thin gel layer on the membrane surface. Such distinction is impossible using only classical hydraulic resistance analysis. The methodology only requires the ratio of microgel to solution conductivity as an input parameter.
理解软纳米粒子的分离、浓缩和纯化过程对于水过滤、生物处理和血液分离等众多应用至关重要。在这里，我们报告了在使用具有微米级孔隙率的膜进行前向过滤时，亚微米级微凝胶的独特迁移和排斥特性。同时测量液压阻力的增加和电阻抗的变化，使我们能够清楚地区分两个沉积阶段：(a) 微凝胶在膜孔隙深度内的积累，以及(b) 随后在膜表面形成薄的凝胶层。仅使用经典的水力阻力分析是不可能做到这一点的。该方法仅需要微凝胶与溶液电导率的比值作为输入参数。
