Kelder B, Chen H, Kopchick J J
Department of Zoological and Biomedical Sciences, Ohio University, Athens 45701.
Gene. 1989 Mar 15;76(1):75-80. doi: 10.1016/0378-1119(89)90009-7.
The induction of the mouse metallothionein-I (MT-I) transcriptional regulatory region by heavy metals in cultured avian cells was studied in a transient-expression assay system for a growth hormone. The MT-I promoter was shown to be inducible by 10 microM to 90 microM ZnCl2 in a dose-dependent manner.