26S蛋白酶体的生命周期：从诞生，历经调控与功能，直至消亡。
The life cycle of the 26S proteasome: from birth, through regulation and function, and onto its death.
作者信息
Livneh Ido, Cohen-Kaplan Victoria, Cohen-Rosenzweig Chen, Avni Noa, Ciechanover Aaron
机构信息
Technion Integrated Cancer Center (TICC), The Rappaport Faculty of Medicine and Research Institute, Haifa, Israel.
出版信息
Cell Res. 2016 Aug;26(8):869-85. doi: 10.1038/cr.2016.86. Epub 2016 Jul 22.
Abstract
The 26S proteasome is a large, ∼2.5 MDa, multi-catalytic ATP-dependent protease complex that serves as the degrading arm of the ubiquitin system, which is the major pathway for regulated degradation of cytosolic, nuclear and membrane proteins in all eukaryotic organisms.
摘要
26S蛋白酶体是一种大型的、约2.5兆道尔顿的多催化ATP依赖性蛋白酶复合体，它作为泛素系统的降解臂，而泛素系统是所有真核生物中细胞质、细胞核和膜蛋白调控降解的主要途径。
Zotero 插件