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妊娠神经病学:病例导向综述

Neurology of Pregnancy: A Case-Oriented Review.

作者信息

O'Neal Mary Angela

机构信息

Department of Neurology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.

出版信息

Neurol Clin. 2016 Aug;34(3):717-31. doi: 10.1016/j.ncl.2016.04.009.

Abstract

The anatomic and physiologic changes that occur during pregnancy are unique. A neurologist needs to be aware of normal pregnancy-induced physiologic changes in the cardiovascular, renal, hematologic, and autoimmune systems, and the local anatomic changes, which include alteration of body habitus and pelvic ligaments. These changes are clearly advantageous, but in certain circumstances may predispose to pathology. In addition, pregnancy effects treatment of chronic neurologic conditions as regards medication safety and metabolism. This case-oriented review discusses the important aspects of pregnancy physiology and an approach to treatment of common disorders encountered during pregnancy including stroke, multiple sclerosis, epilepsy, and compression neuropathies.

摘要

怀孕期间发生的解剖学和生理学变化是独特的。神经科医生需要了解妊娠引起的心血管、肾脏、血液和自身免疫系统的正常生理变化,以及局部解剖学变化,其中包括体型和盆腔韧带的改变。这些变化显然是有益的,但在某些情况下可能易引发病变。此外,妊娠在药物安全性和代谢方面会影响慢性神经疾病的治疗。本以病例为导向的综述讨论了妊娠生理学的重要方面以及治疗妊娠期间常见疾病(包括中风、多发性硬化症、癫痫和压迫性神经病变)的方法。

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