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孤立性硬膜下骨瘤:一例报告及文献综述。

Solitary subdural osteoma: A case report and literature review.

作者信息

Cao Lei, Hong Lichuan, Li Chuzhong, Zhang Yazhuo, Gui Songbai

机构信息

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, P.R. China.

Beijing Neurosurgical Institute, Capital Medical University, Beijing 100050, P.R. China.

出版信息

Oncol Lett. 2016 Aug;12(2):1023-1026. doi: 10.3892/ol.2016.4736. Epub 2016 Jun 16.

Abstract

Osteomas attached to the meninges unrelated to bone are extremely rare and their etiology has not been discussed previously in the English literature. Here, we report the case of a 54-year-old male patient with a right frontal subdural osteoma. The patient presented with a ~5-month history of intermittent dizziness. Non-contrasted computerized tomography demonstrated a densely calcified mass attached to the inner surface of the right frontal skull. Magnetic resonance imaging (MRI) revealed this mass could be enhanced by contrast MRI. Intraoperatively, the hard mass was noted to be attached to the inner layer of the dura mater, and not associated with the bone. Histopathological examination revealed lamellated bony trabeculae lined by osteoblasts and the intertrabecular marrow spaces occupied by adipose tissue, which contributed to the MRI enhancement. It was speculated that subdural osteomas arose from ectopic osteoblasts derived from the embryological neural crest cells. The context of intertrabecular bone marrow contributed to the enhancement on MRI. Simple excision is the treatment of choice for symptomatic lesions.

摘要

附着于脑膜且与骨无关的骨瘤极为罕见,其病因在英文文献中此前尚未有过讨论。在此,我们报告一例54岁男性患者患有右侧额部硬膜下骨瘤的病例。该患者有大约5个月的间歇性头晕病史。非增强计算机断层扫描显示一个致密钙化肿块附着于右侧额颅骨内表面。磁共振成像(MRI)显示该肿块在增强MRI时可强化。术中发现坚硬肿块附着于硬脑膜内层,与骨无关。组织病理学检查显示有成骨细胞排列的板层状骨小梁,小梁间骨髓间隙被脂肪组织占据,这导致了MRI增强。据推测,硬膜下骨瘤起源于胚胎神经嵴细胞衍生的异位成骨细胞。小梁间骨髓的情况导致了MRI上的强化。对于有症状的病变,单纯切除是首选治疗方法。

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CT and pathologic findings of a case of subdural osteoma.1例硬脑膜下骨瘤的CT及病理表现
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