负责抗血管内皮生长因子玻璃体内注射给药的专科护士。
Nurse specialists for the administration of anti-vascular endothelial growth factor intravitreal injections.
作者信息
Samalia Priya, Garland David, Squirrell David
机构信息
Ophthalmology Department, Dunedin Public Hospital, 201 Great King Street, Dunedin, New Zealand.
Department of Ophthalmology, Greenlane Clinical Centre, Auckland, New Zealand.
出版信息
N Z Med J. 2016 Jul 15;129(1438):32-8.
AIM
The number of individuals with chronic conditions such as age-related macular degeneration (AMD) is increasing, and consequently the treatment burden for anti-vascular endothelial growth factor (anti-VEGF) intravitreal injections is also increasing. The use of nurse specialists to administer anti-VEGF intravitreal injections has been proposed to address this treatment burden. This was a prospective safety audit to determine the safety of nurse specialists for the delivery of anti-VEGF intravitreal injections.
METHOD
A prospective safety audit was undertaken for a nurse specialist-delivered injection service in the Ophthalmology Clinic, Greenlane Clinical Centre. The department's senior medical retinal consultant supervised the nurse specialist training programme. The clinical safety of anti-VEGF intravitreal injections delivered by nurse specialists, and the impact of this programme on clinical capacity at our Institute was reviewed.
RESULTS
The nurse specialists administered a total of 2,900 injections over an 18-month period. Two patients developed endophthalmitis post injection (1 infective, 1 non-infective). Two patients had a vitreous haemorrhage, and five patients had raised intraocular pressure. The incidence of post-injection endophthalmitis, vitreous haemorrhage and raised intraocular pressure was 0.07%, 0.07% and 0.17%, respectively.
CONCLUSION
The nurse specialist-delivered injection service is a safe and effective service for treatment of wet AMD, diabetic macular oedema and vein occlusion.
目的
患有年龄相关性黄斑变性（AMD）等慢性病的人数正在增加，因此抗血管内皮生长因子（抗VEGF）玻璃体内注射的治疗负担也在增加。有人提议使用专科护士进行抗VEGF玻璃体内注射，以减轻这种治疗负担。这是一项前瞻性安全性审计，旨在确定专科护士进行抗VEGF玻璃体内注射的安全性。
方法
对格林莱恩临床中心眼科诊所由专科护士提供的注射服务进行了前瞻性安全性审计。该部门的资深视网膜医学顾问监督专科护士培训项目。审查了专科护士进行抗VEGF玻璃体内注射的临床安全性，以及该项目对我们研究所临床能力的影响。
结果
在18个月的时间里，专科护士共注射了2900次。两名患者注射后发生眼内炎（1例感染性，1例非感染性）。两名患者发生玻璃体积血，五名患者眼压升高。注射后眼内炎、玻璃体积血和眼压升高的发生率分别为0.07%、0.07%和0.17%。
结论
由专科护士提供的注射服务是治疗湿性AMD、糖尿病性黄斑水肿和静脉阻塞的一种安全有效的服务。
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