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药物递送方法在宫颈癌治疗中的应用。

Drug Delivery Approaches for the Treatment of Cervical Cancer.

机构信息

Department of Radiation Oncology, Cancer Biology Division, Washington University School of Medicine, Saint Louis, MO 63108, USA.

Department of Medicine, Mount Auburn Hospital, Harvard Medical School, Cambridge, MA 02138, USA.

出版信息

Pharmaceutics. 2016 Jul 20;8(3):23. doi: 10.3390/pharmaceutics8030023.

DOI:10.3390/pharmaceutics8030023
PMID:27447664
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5039442/
Abstract

Cervical cancer is a highly prevalent cancer that affects women around the world. With the availability of new technologies, researchers have increased their efforts to develop new drug delivery systems in cervical cancer chemotherapy. In this review, we summarized some of the recent research in systematic and localized drug delivery systems and compared the advantages and disadvantages of these methods.

摘要

宫颈癌是一种在全球范围内影响女性的高发癌症。随着新技术的出现，研究人员加大了开发宫颈癌化疗中新的药物递送系统的力度。在这篇综述中，我们总结了一些最近在系统性和局部性药物递送系统方面的研究，并比较了这些方法的优缺点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e27/5039442/56d68d8ab3a8/pharmaceutics-08-00023-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e27/5039442/fc37a7d58902/pharmaceutics-08-00023-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e27/5039442/39a43a49ede7/pharmaceutics-08-00023-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e27/5039442/56d68d8ab3a8/pharmaceutics-08-00023-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e27/5039442/fc37a7d58902/pharmaceutics-08-00023-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e27/5039442/39a43a49ede7/pharmaceutics-08-00023-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e27/5039442/56d68d8ab3a8/pharmaceutics-08-00023-g003.jpg

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[1]
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[3]
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[4]
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[5]
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[7]
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[8]
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[9]
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[10]
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[7]
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[8]
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[10]
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本文引用的文献

[1]
Rational design and fabrication of a cancer-targeted chitosan nanocarrier to enhance selective cellular uptake and anticancer efficacy of selenocystine.

J Mater Chem B. 2015-3-28

[2]
Aptamer Functionalized Cisplatin-Albumin Nanoparticles for Targeted Delivery to Epidermal Growth Factor Receptor Positive Cervical Cancer.

J Biomed Nanotechnol. 2016-4

[3]
Anti-cancer activity of doxorubicin-loaded liposomes co-modified with transferrin and folic acid.

Eur J Pharm Biopharm. 2016-6-2

[4]
Small Molecules for Active Targeting in Cancer.

Med Res Rev. 2016-3-15

[5]
Stability, Pharmacokinetics, Biodistribution and Safety Assessment of Folate-Conjugated Pullulan Acetate Nanoparticles as Cervical Cancer Targeted Drug Carriers.

J Nanosci Nanotechnol. 2015-9

[6]
IL-6 Antibody and RGD Peptide Conjugated Poly(amidoamine) Dendrimer for Targeted Drug Delivery of HeLa Cells.

J Phys Chem B. 2016-1-14

[7]
Folate-decorated poly(3-hydroxybutyrate-co-3-hydroxyoctanoate) nanoparticles for targeting delivery: optimization and in vivo antitumor activity.

Drug Deliv. 2015-12-11

[8]
Enhanced Antiproliferative Effect of Carboplatin in Cervical Cancer Cells Utilizing Folate-Grafted Polymeric Nanoparticles.

Nanoscale Res Lett. 2015-12

[9]
3D tissue-engineered bone marrow as a novel model to study pathophysiology and drug resistance in multiple myeloma.

Biomaterials. 2015-12

[10]
Promising potency of retinoic acid-poly(ethylene glycol)-thiol gold nanoparticle conjugates for cervical cancer treatment.

Int J Clin Exp Med. 2015-7-15

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