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老年严重骨盆骨折多发伤患者的临床表现:与年轻成年患者的比较。

Clinical presentation of geriatric polytrauma patients with severe pelvic fractures: comparison with younger adult patients.

作者信息

Kanezaki Shozo, Miyazaki Masashi, Notani Naoki, Tsumura Hiroshi

机构信息

Department of Orthopaedic Surgery, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu-Shi, Oita, 879-5593, Japan.

出版信息

Eur J Orthop Surg Traumatol. 2016 Dec;26(8):885-890. doi: 10.1007/s00590-016-1822-7. Epub 2016 Jul 22.

Abstract

BACKGROUND

Elderly polytrauma patients with pelvic fractures are at higher risk than young adults for severe medical outcomes and/or death in the early post-trauma phase. The aim of our study was to identify predictive factors of medical severity among geriatric polytrauma patients.

METHODS

We conducted a retrospective cross-sectional study of polytrauma patients treated at our center, who had a pelvic fracture and at least two other injuries with an abbreviated injury score ≥3. Our study group included 15 geriatric (mean age, 65 years) and 13 young (mean age, 39 years) adults. Factors related to medical status on admission were compared between the groups to identify those predictive of a severe medical outcome, defined by massive transfusion (>10 units of red blood cells) within the first 24 h of admission and/or death.

RESULTS

Groups were comparable in terms of injury severity score (mean, 29), systolic blood pressure, heart rate, shock index, hemoglobin level, the prothrombin time-to-international normalized ratio (PT-INR) and base deficit. Over two-third of geriatric patients required a massive transfusion, with two patients dying, compared with the death of one young patient. Among geriatric patients, predictors of a severe medical outcome were extravasation of contrast medium on computed tomography, a hemoglobin level <11 g/dl, a PT-INR >1.1 and a base deficit >2 mmol/l.

CONCLUSIONS

Even with our aggressive treatment algorism of pelvic fractures, particularly for the elderly, most of the geriatric polytrauma patients with severe pelvic fractures were at a high risk of massive transfusion. Extravasation on enhanced computed tomography and abnormal levels of select blood serum markers could assist in the early identification of geriatric polytrauma patients at risk for a severe medical outcome.

摘要

背景

老年多发伤伴骨盆骨折患者在创伤后早期出现严重医疗后果和/或死亡的风险高于年轻成年人。我们研究的目的是确定老年多发伤患者医疗严重程度的预测因素。

方法

我们对在本中心接受治疗的多发伤患者进行了一项回顾性横断面研究,这些患者伴有骨盆骨折且至少有另外两处损伤,简明损伤定级标准(AIS)≥3分。我们的研究组包括15名老年患者(平均年龄65岁)和13名年轻患者(平均年龄39岁)。比较两组入院时与医疗状况相关的因素,以确定那些可预测严重医疗后果的因素,严重医疗后果定义为入院后24小时内大量输血(>10单位红细胞)和/或死亡。

结果

两组在损伤严重程度评分(平均29分)、收缩压、心率、休克指数、血红蛋白水平、凝血酶原时间国际标准化比值(PT-INR)和碱缺失方面具有可比性。超过三分之二的老年患者需要大量输血,两名患者死亡,而年轻患者中有一名死亡。在老年患者中,严重医疗后果的预测因素是计算机断层扫描造影剂外渗、血红蛋白水平<11g/dl、PT-INR>1.1和碱缺失>2mmol/l。

结论

即使采用我们积极的骨盆骨折治疗方案,尤其是对老年人,大多数伴有严重骨盆骨折的老年多发伤患者仍有大量输血的高风险。增强计算机断层扫描造影剂外渗和特定血清标志物水平异常有助于早期识别有严重医疗后果风险的老年多发伤患者。

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