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关于孕期及哺乳期潜在接触致畸物情况致电致畸物信息服务机构。

Calls to a teratogen information service regarding potential exposures in pregnancy and breastfeeding.

作者信息

Campbell Sarah C, Kast Tyler T, Kamyar Manijeh, Robertson Julia, Sherwin Catherine M

机构信息

Nelson Laboratories, Salt Lake City, UT, USA.

Department of Pharmacology and Toxicology, College of Pharmacy, University of Utah, Salt Lake City, UT, USA.

出版信息

BMC Pharmacol Toxicol. 2016 Jul 23;17(1):33. doi: 10.1186/s40360-016-0076-7.

Abstract

BACKGROUND

MotherToBaby Utah is a teratogen information service that provides support for pregnant and breastfeeding women and healthcare providers regarding risks of exposures to medications, infections, herbals, homeopathic and dietary medications, chemicals and other substances. Calls are anonymous and free of charge. This study was undertaken to examine the volume and classification of calls regarding exposures during pregnancy and breastfeeding.

METHODS

Data were extracted from calls requesting information about medication use and other exposures to pregnant and breastfeeding women, between January 1 2009 and December 31 2012. Descriptive statistics were calculated.

RESULTS

A total of 27,299 calls regarding 46,031 exposures were identified in this study population. The majority of calls were made by the exposed individual (82.1 %); 13.0 % were made by a healthcare provider and 4.9 % were made by a family member or acquaintance. The majority of calls concerned pregnancy (65.8 %) versus breastfeeding (34.2 %). Exposure during the current pregnancy was the subject of 88.6 % of calls. For calls where trimester information was available, the percentage of calls for first, second and third trimesters were 44.1, 32.5 and 23.4 %, respectively.

CONCLUSION

This study found analgesics, cold medications, herbals, homeopathic, and dietary medications were of the topic of concern for the majority of the calls regarding exposure during pregnancy and/or breastfeeding. Teratogen information services gather and provide important educational resources for both patients and healthcare providers. As the majority of calls concern nonprescription drugs and vaccines, these data provide insight into a lack of education on these subjects that should be addressed during prenatal care.

摘要

背景

犹他州母婴健康咨询服务中心是一家致畸物信息服务机构,为孕妇、哺乳期妇女及医疗服务提供者提供有关药物、感染、草药、顺势疗法及膳食补充剂、化学品和其他物质暴露风险的咨询服务。咨询电话匿名且免费。本研究旨在调查孕期及哺乳期暴露相关咨询电话的数量及分类情况。

方法

提取2009年1月1日至2012年12月31日期间,为孕妇及哺乳期妇女提供药物使用及其他暴露相关信息的咨询电话数据,并进行描述性统计分析。

结果

本研究共识别出27299个咨询电话,涉及46031次暴露。大多数咨询电话由暴露个体拨打(82.1%);13.0%由医疗服务提供者拨打,4.9%由家庭成员或熟人拨打。大多数咨询电话涉及孕期(65.8%)而非哺乳期(34.2%)。当前孕期暴露是88.6%咨询电话的主题。对于可获取孕期信息的咨询电话,第一、二、三期的咨询电话百分比分别为44.1%、32.5%和23.4%。

结论

本研究发现,镇痛药、感冒药、草药、顺势疗法及膳食补充剂是孕期和/或哺乳期暴露相关咨询电话中最受关注的话题。致畸物信息服务机构为患者和医疗服务提供者收集并提供重要的教育资源。由于大多数咨询电话涉及非处方药和疫苗,这些数据揭示了产前护理中应解决的这些主题教育的不足。

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