Ritchie Helen Elizabeth, Oakes Diana Joy, Hegedus Elizabeth, Hill Majella, Kennedy Debra
Discipline of Biomedical Science, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
Mothersafe, The Royal Hospital for Women, Sydney, New South Wales, Australia.
Aust N Z J Obstet Gynaecol. 2017 Apr;57(2):162-167. doi: 10.1111/ajo.12584. Epub 2017 Mar 9.
MotherSafe is a free telephone-based counselling service for the general public and healthcare providers concerned about exposures during pregnancy and breastfeeding. Calls relating to paternal exposures are less common, but can cause distress to the person concerned. This review seeks to identify the key concerns and what information is available to address these concerns.
To review calls made to MotherSafe about paternal exposures to teratogens during the 16 year period, 2000-2015, and to document any patterns or changes in calls over the period.
A retrospective descriptive assessment of a prospectively collected database (2000-2015) was undertaken. Telephone counselling records identified the drugs of concern regarding paternal exposures. The information about paternal exposures provided in consumer and production information was also reviewed.
Of a total of 253 103 calls received at MotherSafe between 2000 and 2015, 1072 calls (0.4%) were regarding paternal exposures. The majority of these calls related to immunomodifiers (19%), hair loss products (11%) and antidepressant medications.
Paternal exposures represent a small proportion of all the counselling calls made to MotherSafe. The study highlighted the deficient and often misleading information about paternal exposures found in most consumer and product information sheets or via the internet. The study indicates the important role of Teratogen Information Services like Mothersafe in providing evidence-based information to both consumers and healthcare providers.
MotherSafe是一项免费的电话咨询服务，面向关注孕期和哺乳期接触情况的普通公众及医疗服务提供者。与父亲接触相关的咨询电话较少见，但可能会使相关人员感到困扰。本综述旨在确定主要关注点以及有哪些信息可用于解决这些问题。
回顾2000年至2015年这16年间拨打给MotherSafe关于父亲接触致畸剂的咨询电话，并记录这段时间内咨询电话的任何模式或变化。
对前瞻性收集的数据库（2000 - 2015年）进行回顾性描述性评估。电话咨询记录确定了与父亲接触相关的关注药物。还对消费者和产品信息中提供的有关父亲接触的信息进行了审查。
2000年至2015年期间，MotherSafe共接到253103个咨询电话，其中1072个（0.4%）与父亲接触有关。这些电话大多数涉及免疫调节剂（19%）、脱发产品（11%）和抗抑郁药物。
父亲接触相关咨询电话在拨打给MotherSafe的所有咨询电话中占比很小。该研究突出了在大多数消费者和产品信息单或通过互联网上发现的关于父亲接触的信息存在不足且常常具有误导性。该研究表明像MotherSafe这样的致畸剂信息服务机构在为消费者和医疗服务提供者提供循证信息方面的重要作用。
