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腹腔镜治疗子宫角部异位妊娠:一种不同的技术。

Laparoscopic Management of Heterotopic Istmocornual Pregnancy: A Different Technique.

作者信息

Peker Nuri, Aydeniz Elif Ganime, Gündoğan Savaş, Şendağ Fatih

机构信息

Department of Obstetrics and Gynecology, Acibadem University Atakent Hospital, Istanbul, Turkey.

Department of Obstetrics and Gynecology, Acibadem University Atakent Hospital, Istanbul, Turkey.

出版信息

J Minim Invasive Gynecol. 2017 Jan 1;24(1):8-9. doi: 10.1016/j.jmig.2016.07.008. Epub 2016 Jul 20.

Abstract

STUDY OBJECTIVE

To present a modified technique for laparoscopic cornual resection for the surgical treatment of heterotopic istmocornual pregnancy.

DESIGN

A step-by-step explanation of the surgery using video (Canadian Task Force Classification III-c).

SETTING

Heterotopic pregnancy is the coexistence of pregnancy in both the intrauterine and extrauterine sides. The incidence is 1 in 30 000 in spontaneous pregnancies; however, the incidence increased to 1 in 100 to 1 in 500 pregnancies with the increasing number of artificial reproductive technologies [1,2]. Although management is controversial, there are 2 main approaches classified as surgical and nonsurgical. The administration of potassium chloride, methotrexate, and/or hyperosmolar glucose is a nonsurgical intervention; however, there are some limitations such as systemic side effects and the possible adverse effect on a live fetus [1-3]. For this reason, surgical intervention involving cornual resection is the main treatment option.

CASE REPORT

A 32-year-old patient was admitted to our clinic with sudden-onset pain at the left groin. She was at the 11th week of gestation. She had a diagnosis of infertility for 7 years, and she became pregnant after an in vitro fertilization cycle. At sonographic examination, 2 gestational sacs were detected, 1 with a live fetus settled into the uterus and the second (20-mm length) on the left cornual side without a yolk sac and embryo and the left adnexa accompanied with coagulated blood. Immediate laparoscopic surgery was planned. At the laparoscopic exploration, left istmocornual pregnancy that was ruptured and bleeding were observed. We performed a modified technique for laparoscopic cornual resection in which the uterine corn was tightened with the noose twice, and the corn was sutured circularly to avoid excessive bleeding. Initially, the mesosalpinx was coagulated and transected with bipolar energy. Afterward, the uterine corn was tightened with the noose twice, and the fallopian tube was removed. To reduce the bleeding during remnant cornual tissue extraction, a permanent 0 monofilament suture was passed deep into the myometrium and tightened to achieve better hemostasis. Then, the remnant cornual tissue was extracted with harmonic scissors, and the uterine wound was repaired with continuous suture to reduce the risk of uterine rupture during the ongoing pregnancy. Depot progesterone was administered just before the surgery and the day after. She was discharged on the first postoperative day. At the follow-up, she did not experience any problems during pregnancy, and she was delivered with cesarean section at 39 weeks' gestation.

CONCLUSION

In conclusion, laparoscopic surgery is a safe and feasible option for the treatment of heterotopic pregnancy, and control of bleeding can be achieved better with our modified technique.

摘要

研究目的

介绍一种改良的腹腔镜子宫角切除术技术,用于异位峡部子宫角妊娠的手术治疗。

设计

使用视频对手术进行逐步讲解(加拿大工作组分类III - c)。

背景

异位妊娠是指子宫内和子宫外同时存在妊娠。自然妊娠中的发生率为1/30000;然而,随着人工生殖技术使用数量的增加,其发生率在妊娠中升至1/100至1/500[1,2]。尽管治疗存在争议,但主要有手术和非手术两种主要方法。氯化钾、甲氨蝶呤和/或高渗葡萄糖的给药是非手术干预;然而,存在一些局限性,如全身副作用以及对存活胎儿可能产生的不良影响[1 - 3]。因此,涉及子宫角切除术的手术干预是主要的治疗选择。

病例报告

一名32岁患者因左腹股沟突然疼痛入院。她处于妊娠第11周。她有7年不孕诊断史,在体外受精周期后怀孕。超声检查发现2个妊娠囊,1个有存活胎儿位于子宫内,另一个(长20毫米)位于左侧子宫角,无卵黄囊和胚胎,左侧附件伴有凝血。计划立即进行腹腔镜手术。在腹腔镜探查中,观察到左侧峡部子宫角妊娠破裂并出血。我们进行了改良的腹腔镜子宫角切除术,用套索将子宫角收紧两次,然后环形缝合子宫角以避免过多出血。首先,用双极能量凝固并横断输卵管系膜。之后,用套索将子宫角收紧两次,切除输卵管。为减少残留子宫角组织切除过程中的出血,将一根永久性0号单丝缝线深入肌层并收紧以实现更好的止血。然后,用超声刀切除残留的子宫角组织,并用连续缝线修复子宫伤口,以降低继续妊娠期间子宫破裂的风险。术前及术后第一天给予长效孕激素。她术后第一天出院。随访期间,她在妊娠期间未出现任何问题,并在妊娠39周时行剖宫产分娩。

结论

总之,腹腔镜手术是治疗异位妊娠的一种安全可行的选择,采用我们的改良技术可以更好地控制出血。

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