离子溅射式脑积水分流器的体外流量测量

In vitro flow measurements in ion sputtered hydrocephalus shunts.

作者信息

Cho Y I, Back L H

机构信息

Jet Propulsion Laboratory, California Institute of Technology, Pasadena 91109.

出版信息

J Biomech. 1989;22(4):335-42. doi: 10.1016/0021-9290(89)90047-x.

DOI:10.1016/0021-9290(89)90047-x

PMID:2745467

Abstract

Accurate in vitro measurements of the pressure drop-flow (drainage) rate relationship were made for perforated Teflon microtubules using a fish hook arrangement. These measurements indicated that appropriate drainage rates could be obtained in the physiological range for hydrocephalus shunts. Animal experimentation is required for in vivo evaluation of these microtubules with micron-sized holes that may prevent cellular ingrowth and recurrent obstruction, and thus extend implanted shunt life.

摘要

使用鱼钩装置对多孔聚四氟乙烯微管进行了压降-流量（引流）率关系的精确体外测量。这些测量表明，在脑积水分流器的生理范围内可以获得合适的引流率。对于这些带有微米级小孔的微管，需要进行动物实验以进行体内评估，这些小孔可能会阻止细胞向内生长和反复阻塞，从而延长植入分流器的使用寿命。