腋窝淋巴结分期中磁共振计算机辅助评估假阴性和假阳性结果的危险因素
Risk Factors for False-Negative and False-Positive Results of Magnetic Resonance Computer-Aided Evaluation in Axillary Lymph Node Staging.
作者信息
Yun Seong Jong, Sohn Yu-Mee, Seo Mirinae
机构信息
From the *Department of Medicine, Graduate School, Kyung Hee University; and †Department of Radiology, Kyung Hee University Hospital, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
出版信息
J Comput Assist Tomogr. 2016 Nov/Dec;40(6):928-936. doi: 10.1097/RCT.0000000000000463.
PURPOSE
The aims of this study were to investigate the false-negative and false-positive results on magnetic resonance (MR) computer-aided evaluation (CAE) in axillary lymph node (ALN) staging and to evaluate the related factors in patients with invasive breast cancer.
METHODS
From July 2011 to May 2014, 103 invasive breast cancer patients who underwent preoperative MR-CAE were included. False MR-CAE results in ALN staging were compared in terms of clinicopathologic features, baseline mammography, and breast ultrasonography. Logistic regression analyses were used to evaluate independent factors related to false results.
RESULTS
For MR-CAE, the false-negative and false-positive results of ALN metastasis were 6.8% and 33.3%, respectively. On multivariate analysis, spiculated tumor margin (P = 0.016) and positive lymphovascular invasion (P = 0.020) were associated with false-negative results, and circumscribed tumor margin (P = 0.017) and negative lymphovascular invasion (P = 0.036) were associated with false-positive results for ALN metastasis.
CONCLUSIONS
Tumor margin and lymphovascular invasion are the key factors that affect the false MR-CAE results in ALN staging.
目的
本研究旨在调查磁共振（MR）计算机辅助评估（CAE）在腋窝淋巴结（ALN）分期中的假阴性和假阳性结果，并评估浸润性乳腺癌患者的相关因素。
方法
纳入2011年7月至2014年5月期间接受术前MR-CAE的103例浸润性乳腺癌患者。根据临床病理特征、基线乳腺X线摄影和乳腺超声检查，比较ALN分期中MR-CAE的假结果。采用逻辑回归分析评估与假结果相关的独立因素。
结果
对于MR-CAE，ALN转移的假阴性和假阳性结果分别为6.8%和33.3%。多因素分析显示，毛刺状肿瘤边缘（P = 0.016）和阳性淋巴管浸润（P = 0.020）与假阴性结果相关，而边界清晰的肿瘤边缘（P = 0.017）和阴性淋巴管浸润（P = 0.036）与ALN转移的假阳性结果相关。
结论
肿瘤边缘和淋巴管浸润是影响MR-CAE在ALN分期中出现假结果的关键因素。
Zotero 插件