Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
Curr Biol. 2016 Jul 25;26(14):R683-5. doi: 10.1016/j.cub.2016.05.034.
Bacterial CRISPR-Cas systems acquire short sequences, called spacers, from viruses and plasmids, leading to adaptive immunity. The diversity of spacers within natural bacterial populations is very high. New data now explain how spacer diversity strengthens resistance of the bacterial population to phage infection.
细菌的 CRISPR-Cas 系统从病毒和质粒中获取短序列，称为间隔序列，从而产生适应性免疫。天然细菌种群中间隔序列的多样性非常高。新数据现在解释了间隔序列多样性如何增强细菌种群对噬菌体感染的抵抗力。
