Bercin Sami, Yalciner Gokhan, Muderris Togay, Gul Fatih, Deger H Mervan, Kiris Muzaffer
Department of Otorhinolaryngology, Head and Neck Surgery, Yıldırım Beyazıt University School of Medicine, Ankara, Turkey.
Department of Otorhinolaryngology, Head and Neck Surgery, Ataturk Training and Research Hospital, Ankara, Turkey.
Clin Exp Otorhinolaryngol. 2017 Sep;10(3):283-287. doi: 10.21053/ceo.2015.01256. Epub 2016 Jul 27.
To retrospectively evaluate the patients who underwent nasopharyngeal biopsy with imaging and biopsy results, who have or don't have symptoms for nasopharyngeal pathology and to determine the ratio of the nasopharyngeal cancer cases and other pathologic conditions.
In this retrospective study, 983 patients who underwent endoscopic nasopharyngeal biopsy for symptomatic nasopharyngeal lesions were included. All pathological results, benign or malign was recorded and classified due to the patients' presenting symptoms such as symptomatic for nasopharyngeal pathology or asymptomatic. Computed tomography (CT) or magnetic resonance imaging (MRI) reports were also recorded separately as group A for malignancy or group B for not malignancy.
Forty-five (4.6%) of 983 biopsies were malignant. In this group, there is no statistically significant difference between symptomatic and asymptomatic group. For malignant pathologies, the sensitivity of MRI was found 88.2% and CT was 61.5%.
For early diagnosis of nasopharyngeal cancer, all patients admitted to Ear, Nose and Throat (ENT) referral clinics should be examined endoscopically irrespective of their complaints and suspicious cases should be investigated by imaging especially by MRI. If MRI report clearly indicates Thornwaldt cyst or reactive lymphoid hyperplasia and this result is compatible with endoscopic findings, biopsy may not be necessary. Apart from these cases, all suspected lesions should be biopsied.
回顾性评估接受鼻咽活检的患者的影像学和活检结果，这些患者有或没有鼻咽部病变症状，并确定鼻咽癌病例与其他病理情况的比例。
在这项回顾性研究中，纳入了983例因鼻咽部有症状性病变而接受鼻内镜下鼻咽活检的患者。记录所有病理结果，无论良性或恶性，并根据患者的症状进行分类，如鼻咽部病变有症状或无症状。计算机断层扫描（CT）或磁共振成像（MRI）报告也分别记录为A组（恶性）或B组（非恶性）。
983例活检中有45例（4.6%）为恶性。在该组中，有症状组和无症状组之间无统计学显著差异。对于恶性病变，MRI的敏感性为88.2%，CT为61.5%。
为了早期诊断鼻咽癌，所有转诊至耳鼻喉科门诊的患者都应接受内镜检查，无论其主诉如何，可疑病例应进行影像学检查，尤其是MRI检查。如果MRI报告明确显示为托恩瓦尔德特囊肿或反应性淋巴组织增生，且该结果与内镜检查结果相符，则可能无需活检。除这些情况外，所有可疑病变均应进行活检。
