Shrivastava Saurabh RamBihariLal, Shrivastava Prateek Saurabh, Ramasamy Jegadeesh
Department of Community Medicine, Shri Sathya Sai Medical College and Research Institute, Ammapettai, Chennai, Tamil Nadu, India.
J Cancer Res Ther. 2016 Apr-Jun;12(2):493-7. doi: 10.4103/0973-1482.146116.
The aim of the current review is to assess the magnitude of the breast cancer, and to explore the contribution of different dietary constituents in both the causation and the prevention of the disease. An exhaustive search for all materials related to the topic was made in different search engines, including PubMed, World Health Organization Web site, and Google scholar, for a duration of 30 days (June 2014). Relevant documents, systematic reviews, technical publication series, research articles, books, and guidelines focusing on the association of dietary factors and breast cancer, published in 1998-2014 were included in the review. Overall, 56 articles were selected based on the suitability with the current review objectives and analyzed. Although specific foods and nutrients have been attributed to the causation of breast cancer, the association of the same with overall diet is still inconsistent and unexplored. As the etiology of breast cancer is multifactorial and because contribution of each factor in the development of the disease is still unclear, early detection of the disease remains the crucial factor in breast cancer control. To conclude, a definite direct or inverse association has been observed in the development of breast cancer with the dietary nutrients, and thus there is an urgent need to develop cost-effective and readily available approach for the early detection and treatment of breast cancer, especially among women from low-resource settings.
本次综述的目的是评估乳腺癌的规模，并探讨不同饮食成分在该疾病的病因和预防方面的作用。在不同的搜索引擎中，包括PubMed、世界卫生组织网站和谷歌学术，对与该主题相关的所有材料进行了为期30天（2014年6月）的详尽搜索。纳入综述的文献包括1998年至2014年期间发表的、聚焦于饮食因素与乳腺癌关联的相关文献、系统评价、技术出版物系列、研究文章、书籍及指南。总体而言，根据与当前综述目标的契合度，挑选出56篇文章并进行了分析。尽管特定食物和营养素被认为与乳腺癌的病因有关，但它们与总体饮食的关联仍不一致且未得到充分研究。由于乳腺癌的病因是多因素的，且每个因素在疾病发展中的作用仍不明确，因此疾病的早期检测仍然是乳腺癌控制的关键因素。总之，在乳腺癌的发展过程中，已观察到饮食营养素与乳腺癌之间存在明确的直接或反向关联，因此迫切需要开发具有成本效益且易于获得的方法，用于乳腺癌的早期检测和治疗，尤其是在资源匮乏地区的女性中。
