混乱、儿茶酚-O-甲基转移酶与儿童社会行为：挪威关于混乱依恋遗留影响的假说
Disorganization, COMT, and Children's Social Behavior: The Norwegian Hypothesis of Legacy of Disorganized Attachment.
作者信息
Li Zhi, Hygen Beate W, Widaman Keith F, Berg-Nielsen Turid S, Wichstrøm Lars, Belsky Jay
机构信息
Department of Human Ecology, University of California, Davis Davis, CA, USA.
NTNU Social ScienceTrondheim, Norway; Department of Psychology, Norwegian University of Science and TechnologyTrondheim, Norway.
出版信息
Front Psychol. 2016 Jul 12;7:1013. doi: 10.3389/fpsyg.2016.01013. eCollection 2016.
Why is disorganized attachment associated with punitive-controlling behavior in some, but caregiving-controlling in others? Hygen et al. (2014) proposed that variation in the Catechol-O-methyl transferase(COMT) Val158Met genotype explains this variation, providing preliminary data to this effect. We offer a conceptual replication, analyzing data on 560 children (males: 275) drawn from the NICHD Study of Early Child Care and Youth Development. As predicted, competitive model-fitting indicated that disorganized infants carrying Met alleles engage in more positive behavior and less negative behavior than other children at age 5 and 11, with the reverse true of Val/Val homozygotes, seemingly consistent with caregiving-controlling and punitive-controlling styles, respectively, but only in the case of maternal and not teacher reports, thereby confirmating a relationship-specific hypothesis.
为什么混乱型依恋在一些情况下与惩罚性控制行为相关，而在另一些情况下却与照顾性控制行为相关？海根等人（2014年）提出，儿茶酚-O-甲基转移酶（COMT）Val158Met基因分型的差异可以解释这种变化，并提供了相关的初步数据。我们进行了一项概念性重复研究，分析了来自国家儿童健康与人类发展研究所早期儿童保育与青少年发展研究的560名儿童（男童：275名）的数据。正如预测的那样，竞争性模型拟合表明，携带Met等位基因的混乱型婴儿在5岁和11岁时比其他儿童表现出更多积极行为和更少消极行为，而Val/Val纯合子则相反，这似乎分别与照顾性控制和惩罚性控制风格一致，但仅在母亲报告而非教师报告的情况下如此，从而证实了一个特定关系的假设。
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