Department of Medicine, Division of Cardiology, New York University School of Medicine, New York.
Department of Statistics, New York University School of Medicine, New York.
JAMA Cardiol. 2016 Sep 1;1(6):640-7. doi: 10.1001/jamacardio.2016.0785.
Reduced rates of cardiac catheterization, percutaneous coronary intervention (PCI), and coronary artery bypass graft (CABG) are an unintended consequence of public reporting of cardiogenic shock outcomes in New York.
To evaluate whether the referral rates for cardiac catheterization, PCI, or CABG have improved in New York since cardiogenic shock was excluded from public reporting in 2008 and compare them with corresponding rates in Michigan, New Jersey, and California.
DESIGN, SETTING, AND PARTICIPANTS: Patients with cardiogenic shock complicating acute myocardial infarction from 2002 to 2011 were identified using the National Inpatient Sample. Propensity score matching was used to assemble a cohort of patients with cardiogenic shock with similar baseline characteristics in New York and Michigan.
Percutaneous coronary intervention (primary outcome), invasive management (cardiac catheterization, PCI, or CABG), revascularization (PCI or CABG), and CABG were evaluated with reference to 3 calendar year periods: 2002-2005 (time 1: cardiogenic shock included in publicly reported outcomes), 2006-2007 (time 2: cardiogenic shock excluded on a trial basis), and 2008 and thereafter (time 3: cardiogenic shock excluded permanently) in New York and compared with Michigan.
Among 2126 propensity score-matched patients representing 10 795 (weighted) patients with myocardial infarction complicated by cardiogenic shock in New York and Michigan, 905 (42.6%) were women and mean (SE) age was 69.5 (0.3) years. A significantly higher proportion of the patients underwent PCI (time 1 vs 2 vs 3: 31.1% vs 39.8% vs 40.7% [OR, 1.50; 95% CI, 1.12-2.01; P = .005 for time 3 vs 1]), invasive management (time 1 vs 2 vs 3: 59.7% vs 70.9% vs 73.8% [OR, 1.84; 95% CI, 1.37-2.47; P < .001 for time 3 vs 1]), or revascularization (43.1% vs 55.9% vs 56.3% [OR, 1.66; 95% CI, 1.26-2.20; P < .001 for time 3 vs 1]) after the exclusion of cardiogenic shock from public reporting in New York. However, during the same periods, a greater proportion of patients underwent PCI (time 1 vs 2 vs 3: 41.2% vs 52.6% vs 57.8% [OR, 1.93; 95% CI, 1.45-2.56; P < .001 for time 3 vs 1]), invasive management (time 1 vs 2 vs 3: 64.4% vs 80.5% vs 78.6% [OR, 2.01; 95% CI, 1.47-2.74; P < .001 for time 3 vs 1]), or revascularization (51.2% vs 65.8% vs 68.0% [OR, 2.00; 95% CI, 1.50-2.66; P < .001 for times 3 vs 1]) in Michigan. Results were largely similar in several sensitivity analyses comparing New York with New Jersey or California.
Although the rates of PCI, invasive management, and revascularization have increased substantially after the exclusion of cardiogenic shock from public reporting in New York, these rates remain consistently lower than those observed in other states without public reporting.
纽约公布心源性休克结果后,心脏导管检查、经皮冠状动脉介入治疗(PCI)和冠状动脉旁路移植术(CABG)的减少率是意料之外的结果。
评估自 2008 年心源性休克从公共报告中排除以来,纽约的心脏导管检查、PCI 或 CABG 的转诊率是否有所改善,并与密歇根州、新泽西州和加利福尼亚州进行比较。
设计、地点和参与者:使用国家住院患者样本,确定了 2002 年至 2011 年急性心肌梗合并心源性休克的患者。使用倾向评分匹配方法,在纽约和密歇根州匹配了一组具有相似基线特征的心源性休克患者。
经皮冠状动脉介入治疗(主要结局)、有创治疗(心脏导管检查、PCI 或 CABG)、血运重建(PCI 或 CABG)和 CABG,参考了纽约的三个日历年度:2002-2005 年(时间 1:心源性休克包含在公开报告的结果中)、2006-2007 年(时间 2:心源性休克在试验基础上被排除)和 2008 年及以后(时间 3:心源性休克被永久排除),并与密歇根州进行了比较。
在 2126 名经倾向评分匹配的患者中,有 10795 名(加权)患有心肌梗合并心源性休克的患者,其中 905 名(42.6%)为女性,平均(SE)年龄为 69.5(0.3)岁。接受 PCI 的患者比例显著更高(时间 1 与时间 2 与时间 3:31.1%与 39.8%与 40.7%[OR,1.50;95%CI,1.12-2.01;P=0.005 时间 3 与时间 1])、有创治疗(时间 1 与时间 2 与时间 3:59.7%与 70.9%与 73.8%[OR,1.84;95%CI,1.37-2.47;P<0.001 时间 3 与时间 1])或血运重建(43.1%与 55.9%与 56.3%[OR,1.66;95%CI,1.26-2.20;P<0.001 时间 3 与时间 1]),在心源性休克从公共报告中排除后,纽约。然而,在同一时期,接受 PCI 的患者比例更高(时间 1 与时间 2 与时间 3:41.2%与 52.6%与 57.8%[OR,1.93;95%CI,1.45-2.56;P<0.001 时间 3 与时间 1])、有创治疗(时间 1 与时间 2 与时间 3:64.4%与 80.5%与 78.6%[OR,2.01;95%CI,1.47-2.74;P<0.001 时间 3 与时间 1])或血运重建(51.2%与 65.8%与 68.0%[OR,2.00;95%CI,1.50-2.66;P<0.001 时间 3 与时间 1])在密歇根州。在将纽约与新泽西州或加利福尼亚州进行的几项敏感性分析中,结果基本相似。
尽管在纽约将心源性休克从公共报告中排除后,PCI、有创治疗和血运重建的比例大幅增加,但这些比例仍明显低于其他没有公共报告的州。