Hattori T, Niwa H
Nihon Jibiinkoka Gakkai Kaiho. 1989 Feb;92(2):221-7. doi: 10.3950/jibiinkoka.92.221.
Evaluation of clinical application of evoked oto-acoustic emission (OAE) as an objective cochlear function test was studied in normal hearing subjects, retrocochlear and cochlear deafness cases. In normal hearing subjects, OAE responses showed good reproducibility while the minimum detectable level of OAE varied between subjects. We found that the interaural difference of minimum detectable level of OAE is the best indicator of cochlear damage. As both OAE and ECochG originate from the hair cells, we compared the behavior of OAE and ECochG in cases with retrocochlear deafness. We found that OAE exhibited the same behaviour as CM in ECochG in these cases. In cases of cochlear deafness, in spite of the recovery of the hearing thresholds to within normal levels, the minimum detectable level of OAE remained at an average of about 4. 4dB higher as compared to normal hearing subjects. This demonstrates that a minimal cochlear damage likely to go undetected by pure tone audiometry is detected by OAE measurement. We conclude that OAE must be added to the growing list of tests in the objective assessment of cochlear function.
在正常听力受试者、蜗后性聋和耳蜗性聋病例中，研究了诱发耳声发射（OAE）作为一种客观耳蜗功能测试的临床应用。在正常听力受试者中，OAE反应显示出良好的可重复性，而OAE的最小可检测水平在受试者之间有所不同。我们发现，OAE最小可检测水平的耳间差异是耳蜗损伤的最佳指标。由于OAE和耳蜗电图（ECochG）均起源于毛细胞，我们比较了蜗后性聋病例中OAE和ECochG的表现。我们发现，在这些病例中，OAE在ECochG中的表现与复合动作电位（CM）相同。在耳蜗性聋病例中，尽管听力阈值恢复到正常水平，但与正常听力受试者相比，OAE的最小可检测水平平均仍高出约4.4dB。这表明，OAE测量可检测到纯音听力测定可能未发现的轻微耳蜗损伤。我们得出结论，在耳蜗功能的客观评估中，OAE必须被添加到越来越多的测试项目中。
