Schmidt S, Lenz A, Eilers H, Helledie N, Krebs D
Women's Hospital University of Bonn, West Germany.
J Perinat Med. 1989;17(1):57-62. doi: 10.1515/jpme.1989.17.1.57.
Laser spectrophotometry with near-infrared light is newly available for clinical application. The equipment consists of a near-infrared datacollection unit (NIRDCU) and apersonal computer. Emission of laser light at wavelengths of 775, 805, 845 and 904 nm is provided by the four laserdiodes of the NIRDCU. By analyzing changes of optical density during laser radiation, information is achieved about the intracellular redoxstate and relative changes of blood volume. During measurement with the system on fetal head we were able to get a first impression of the methods potential. While the application of the laser sensors is still cumbersome, signals providing information of the relative changes of hemoglobine concentrations, relative changes of blood volume and cytochrome aa3 seem achievable. Laser spectrophotometric monitors may become save, low cost and portable instruments for the noninvasive assessment of the biochemical and biophysical status in the fetus.
近红外激光分光光度法现已可用于临床应用。该设备由一个近红外数据采集单元（NIRDCU）和一台个人计算机组成。NIRDCU的四个激光二极管可发射波长为775、805、845和904nm的激光。通过分析激光辐射期间光密度的变化，可获得有关细胞内氧化还原状态和血容量相对变化的信息。在用该系统对胎儿头部进行测量时，我们能够对该方法的潜力有初步印象。虽然激光传感器的应用仍然很麻烦，但似乎可以获得提供血红蛋白浓度相对变化、血容量相对变化和细胞色素aa3信息的信号。激光分光光度监测仪可能会成为用于无创评估胎儿生化和生物物理状态的安全、低成本且便携的仪器。
