Davis R H, Leitner M G, Russo J M, Byrne M E
J Am Podiatr Med Assoc. 1989 Jun;79(6):263-76. doi: 10.7547/87507315-79-6-263.
The authors have evaluated the spectrum of anti-inflammatory activity of A. vera in a number of models of inflammation in the hind paw of the experimental rat induced by kaolin, carrageenan, albumin, dextran, gelatin, and mustard. Croton oil was used in a topical model of inflammation to determine the oral activity and time-dependent dosing of A. vera. The authors found that A. vera was active in all models of inflammation. Of the various irritants tested, A. vera was especially active against gelatin-induced and kaolin-induced edema and, in contrast, had minimal activity when tested against dextran-induced edema. Oral activity of A. vera was demonstrated to be dependent on the presence of anthraquinones. The various irritant-induced edema models provided a broad spectrum of anti-inflammatory activity for A. vera.
作者们在由高岭土、角叉菜胶、白蛋白、右旋糖酐、明胶和芥子诱导的实验大鼠后爪多种炎症模型中评估了库拉索芦荟的抗炎活性谱。巴豆油用于炎症局部模型，以确定库拉索芦荟的口服活性和时间依赖性给药。作者们发现，库拉索芦荟在所有炎症模型中均有活性。在测试的各种刺激物中，库拉索芦荟对明胶诱导的和高岭土诱导的水肿特别有效，相比之下，在测试其对右旋糖酐诱导的水肿时活性最小。已证明库拉索芦荟的口服活性取决于蒽醌的存在。各种刺激物诱导的水肿模型为库拉索芦荟提供了广泛的抗炎活性谱。
