Wiznia Lauren E, Quatrano Nicola A, Mu Euphemia W, Rieder Evan A
*All the authors are affiliated with The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York.
Dermatol Surg. 2017 Feb;43(2):161-172. doi: 10.1097/DSS.0000000000000841.
There are considerable emerging data in the use of lasers and lights to treat onychomycosis and psoriasis of the nail subunit.
We aimed to review all of the medical literature on laser therapy of nail psoriasis and onychomycosis published since 1992.
We performed a PubMed literature search using the search terms "nail," "laser therapy," "laser surgery," "light," with search terms "psoriasis" and "onychomycosis." In addition, we performed extensive MeSH and bibliographic searches as delineated in the manuscript. Because of the poor quality of evidence, we were not able to complete a quantitative review and thus present our findings qualitatively.
Although the trials are small, PDL (595 nm) and IPL with a 550-nm filter demonstrate compelling data in treating nail psoriasis. Laser studies of onychomycosis fall short on many levels. Q-switched Nd:YAG lasers with very short pulse durations and fractionated CO2 demonstrate the most promise for the treatment of onychomycosis.
The data for treating nail psoriasis and onychomycosis with laser and light therapy are rapidly emerging. With increased subject data, improved study methodology, and more precise output parameters, lasers may become an important modality in the treatment of nail psoriasis and onychomycosis.
在使用激光和光治疗指甲亚单位的甲癣和银屑病方面,有大量新出现的数据。
我们旨在回顾自1992年以来发表的所有关于激光治疗指甲银屑病和甲癣的医学文献。
我们使用搜索词“指甲”“激光治疗”“激光手术”“光”以及搜索词“银屑病”和“甲癣”在PubMed上进行文献检索。此外,我们按照稿件中所述进行了广泛的医学主题词(MeSH)和文献检索。由于证据质量较差,我们无法完成定量综述,因此定性地呈现我们的研究结果。
尽管试验规模较小,但脉冲染料激光(595nm)和带有550nm滤光片的强脉冲光在治疗指甲银屑病方面显示出令人信服的数据。关于甲癣的激光研究在许多方面存在不足。脉宽极短的调Q钕:钇铝石榴石激光和分次二氧化碳激光在治疗甲癣方面显示出最大的前景。
激光和光疗法治疗指甲银屑病和甲癣的数据正在迅速涌现。随着受试者数据的增加、研究方法的改进以及输出参数的更加精确,激光可能成为治疗指甲银屑病和甲癣的一种重要方式。