Chandrashekar Byalakere Shivanna, Madura Chandu, Shenoy Chaitra, Chandar Abhijna, Roopa Mysore Seshadri, Narayana Nakka Lakshmi
Department of Dermatology, CUTIS Academy of Cutaneous Sciences, Bengaluru, Karnataka, India.
Department of Dermatosurgery, CUTIS Academy of Cutaneous Sciences, Bengaluru, Karnataka, India.
Indian Dermatol Online J. 2024 Dec 26;16(1):59-71. doi: 10.4103/idoj.idoj_776_24. eCollection 2025 Jan-Feb.
Laser therapy has emerged as an innovative approach for managing various nail conditions, offering precise targeting, minimal invasiveness, and favorable safety profiles. This review analyzes the literature on laser therapy for nail indications, encompassing onychomycosis, nail psoriasis, nail warts, ingrown toenails, onychodystrophy, nail pigmentation disorders, and nail tumors.
PubMed and Google Scholar databases were searched to identify articles on laser therapy using specific key terms related to nail conditions (e.g., onychomycosis, nail psoriasis). Relevant articles were shortlisted based on laser treatment in nail disorders, its mechanisms of action, research outcomes, and clinical applications.
Nd: YAG or CO lasers showed efficacy in onychomycosis by targeting fungal cells. Studies suggest that laser treatments offer comparable results to traditional therapies, often enhancing outcomes when combined with topical agents such as calcipotriol/betamethasone in nail psoriasis. For nail warts, ingrown toenails, onychodystrophy, and nail pigmentation disorders, lasers provide alternative or adjunctive therapies, achieving positive outcomes lesion clearance and symptom improvement. Conclusion: This review underscores the transformative potential of laser therapy in nail disorder management, providing clinicians with innovative treatment alternatives. Nevertheless, further studies are needed to refine protocols, evaluate long-term outcomes and explore its application in specific conditions such as nail tumors.
激光疗法已成为治疗各种指甲疾病的一种创新方法,具有精准靶向、微创性和良好的安全性。本综述分析了有关激光疗法治疗指甲疾病的文献,包括甲癣、指甲银屑病、指甲疣、嵌甲、甲营养不良、指甲色素沉着紊乱和指甲肿瘤。
检索PubMed和谷歌学术数据库,以识别使用与指甲疾病相关的特定关键词(如甲癣、指甲银屑病)的激光疗法文章。根据激光治疗指甲疾病、其作用机制、研究结果和临床应用,筛选出相关文章。
钕:钇铝石榴石(Nd:YAG)或二氧化碳(CO)激光通过靶向真菌细胞显示出对甲癣的疗效。研究表明,激光治疗与传统疗法效果相当,在指甲银屑病中与外用药物(如卡泊三醇/倍他米松)联合使用时,通常能提高疗效。对于指甲疣、嵌甲、甲营养不良和指甲色素沉着紊乱,激光提供了替代或辅助治疗方法,在病变清除和症状改善方面取得了积极成果。结论:本综述强调了激光疗法在指甲疾病管理中的变革潜力,为临床医生提供了创新的治疗选择。然而,需要进一步研究来完善方案、评估长期结果,并探索其在指甲肿瘤等特定疾病中的应用。