• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Aspirin use and bleeding volume in skin cancer patients undergoing surgery: a randomized controlled trial.阿司匹林对接受手术的皮肤癌患者出血量的影响：一项随机对照试验。
Daru. 2016 Jul 28;24(1):20. doi: 10.1186/s40199-016-0159-4.
2
Rationale and design of the PeriOperative ISchemic Evaluation-2 (POISE-2) trial: an international 2 × 2 factorial randomized controlled trial of acetyl-salicylic acid vs. placebo and clonidine vs. placebo in patients undergoing noncardiac surgery.围手术期缺血评估-2（POISE-2）试验的原理和设计：一项在非心脏手术患者中进行的乙酰水杨酸与安慰剂以及可乐定与安慰剂的国际 2×2 析因随机对照试验。
Am Heart J. 2014 Jun;167(6):804-9.e4. doi: 10.1016/j.ahj.2014.01.007. Epub 2014 Feb 22.
3
Complications of cutaneous surgery in patients taking clopidogrel-containing anticoagulation.服用氯吡格雷抗凝药物的患者的皮肤外科手术并发症。
J Am Acad Dermatol. 2011 Sep;65(3):584-591. doi: 10.1016/j.jaad.2011.02.013. Epub 2011 Apr 21.
4
Impact of preoperative maintenance or interruption of aspirin on thrombotic and bleeding events after elective non-cardiac surgery: the multicentre, randomized, blinded, placebo-controlled, STRATAGEM trial.择期非心脏手术后术前阿司匹林维持或中断对血栓和出血事件的影响：多中心、随机、盲法、安慰剂对照、STRATAGEM 试验。
Br J Anaesth. 2011 Dec;107(6):899-910. doi: 10.1093/bja/aer274. Epub 2011 Aug 27.
5
[Ambulatory oral procedures in patients on low-dose aspirin].
Harefuah. 1999 Jan 15;136(2):108-10, 175.
6
Does aspirin administration increase perioperative morbidity in patients with cardiac stents undergoing spinal surgery?对于接受脊柱手术的心脏支架置入患者，服用阿司匹林会增加围手术期发病率吗？
Spine (Phila Pa 1976). 2015 May 1;40(9):629-35. doi: 10.1097/BRS.0000000000000695.
7
Comparison of aspirin plus heparin with heparin alone on asymptomatic perioperative deep vein thrombosis in candidates for elective off-pump coronary artery bypass graft: a randomized clinical trial.择期不停跳冠状动脉旁路移植术患者无症状围手术期深静脉血栓形成中阿司匹林加肝素与单独肝素比较：一项随机临床试验。
Cardiol J. 2013;20(2):139-43. doi: 10.5603/CJ.2013.0026.
8
To continue or discontinue aspirin in the perioperative period: a randomized, controlled clinical trial.继续或停止围手术期阿司匹林：一项随机对照临床试验。
Br J Anaesth. 2010 Mar;104(3):305-12. doi: 10.1093/bja/aeq003.
9
Maintenance of perioperative antiplatelet and anticoagulant therapy for vitreoretinal surgery.维持眼后段手术围手术期抗血小板和抗凝治疗。
Clin Exp Ophthalmol. 2013 May-Jun;41(4):387-95. doi: 10.1111/ceo.12017. Epub 2012 Dec 10.
10
Influence of antiplatelet therapy on cerebral micro-emboli after carotid endarterectomy using postoperative transcranial Doppler monitoring.采用术后经颅多普勒监测评估抗血小板治疗对颈动脉内膜切除术后脑微栓子的影响。
Eur J Vasc Endovasc Surg. 2007 Aug;34(2):135-42. doi: 10.1016/j.ejvs.2007.03.011. Epub 2007 May 23.

引用本文的文献

1
Does Aspirin Increase Risk of Bleeding in Patients Undergoing Skin Lesion Excision: A Systematic Review and Meta-Analysis.阿司匹林会增加接受皮肤病变切除术患者的出血风险吗：一项系统评价和荟萃分析
Plast Reconstr Surg Glob Open. 2025 May 12;13(5):e6768. doi: 10.1097/GOX.0000000000006768. eCollection 2025 May.
2
State of the Evidence for Facial Skin Cancer Reconstruction.皮肤癌重建的证据现状。
Facial Plast Surg. 2023 Jun;39(3):220-229. doi: 10.1055/a-2008-2798. Epub 2023 Jan 5.
3
Perioperative Management of Antiplatelet Therapy: A Systematic Review and Meta-analysis.抗血小板治疗的围手术期管理：一项系统评价和荟萃分析。
Mayo Clin Proc Innov Qual Outcomes. 2022 Oct 21;6(6):564-573. doi: 10.1016/j.mayocpiqo.2022.09.006. eCollection 2022 Dec.
4
Continuation versus discontinuation of antiplatelet therapy for bleeding and ischaemic events in adults undergoing non-cardiac surgery.非心脏手术成年患者抗血小板治疗的继续与停用对出血和缺血事件的影响
Cochrane Database Syst Rev. 2018 Jul 18;7(7):CD012584. doi: 10.1002/14651858.CD012584.pub2.

本文引用的文献

1
Lack of evidence for increased risk of postoperative bleeding after cutaneous surgery in the head and neck in patients taking aspirin.没有证据表明服用阿司匹林的患者在头颈部进行皮肤手术后出血风险会增加。
Br J Oral Maxillofac Surg. 2014 Jul;52(6):527-9. doi: 10.1016/j.bjoms.2014.02.020. Epub 2014 Apr 2.
2
Should more patients continue aspirin therapy perioperatively?: clinical impact of aspirin withdrawal syndrome.更多患者应继续围手术期阿司匹林治疗吗？：阿司匹林停药综合征的临床影响。
Ann Surg. 2012 May;255(5):811-9. doi: 10.1097/SLA.0b013e318250504e.
3
Prospective evaluation of dermatologic surgery complications including patients on multiple antiplatelet and anticoagulant medications.前瞻性评估皮肤科手术并发症，包括正在服用多种抗血小板和抗凝药物的患者。
J Am Acad Dermatol. 2011 Sep;65(3):576-583. doi: 10.1016/j.jaad.2011.02.012. Epub 2011 Jul 22.
4
Bleeding complications in skin cancer surgery are associated with warfarin but not aspirin therapy.皮肤癌手术中的出血并发症与华法林有关，而与阿司匹林治疗无关。
Br J Surg. 2007 Nov;94(11):1356-60. doi: 10.1002/bjs.5864.
5
Surgical resection of cutaneous head and neck lesions: does aspirin use increase hemorrhagic risk?头颈部皮肤病变的手术切除：服用阿司匹林会增加出血风险吗？
Arch Otolaryngol Head Neck Surg. 2006 Nov;132(11):1237-41. doi: 10.1001/archotol.132.11.1237.
6
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.低剂量阿司匹林用于心血管疾病二级预防——围手术期停用后的心血管风险与继续使用时的出血风险——综述与荟萃分析
J Intern Med. 2005 May;257(5):399-414. doi: 10.1111/j.1365-2796.2005.01477.x.
7
Controversies in perioperative management of blood thinners in dermatologic surgery: continue or discontinue?皮肤科手术中血液稀释剂围手术期管理的争议：继续还是停用？
Dermatol Surg. 2004 Aug;30(8):1091-4; discussion 1094. doi: 10.1111/j.1524-4725.2004.30333.x.
8
Serious adverse vascular events associated with perioperative interruption of antiplatelet and anticoagulant therapy.与围手术期抗血小板和抗凝治疗中断相关的严重不良血管事件。
Dermatol Surg. 2002 Nov;28(11):992-8; discussion 998. doi: 10.1046/j.1524-4725.2002.02085.x.

阿司匹林对接受手术的皮肤癌患者出血量的影响：一项随机对照试验。

Aspirin use and bleeding volume in skin cancer patients undergoing surgery: a randomized controlled trial.

作者信息

Engheta Arman, Hadadi Abianeh Shahryar, Atri Ali, Sanatkarfar Mehdi

机构信息

Department of Plastic Surgery, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Department of Plastic Surgery, Razi Hospital, Tehran University of Medical Sciences, Vahdat Eslami st, Tehran, Iran.

出版信息

Daru. 2016 Jul 28;24(1):20. doi: 10.1186/s40199-016-0159-4.

DOI:10.1186/s40199-016-0159-4
PMID:27465859
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4964271/
Abstract

UNLABELLED

ᅟ: We investigated the occurrence of bleeding complications in patients who underwent skin tumor surgery and compared it between Aspirin users and a placebo control group. In this double blind randomized controlled trial, 32 patients who continued taking aspirin (intervention group) and 38 patients who stopped taking Aspirin (placebo group) before surgery were compared in terms of intraoprative and postoperative bleeding problems, hematoma and local signs of coagulopathy. There was no statistically significant difference in intraoprative bleeding between the study groups (P = 0.107). We concluded that continuation of Aspirin therapy had no significant effect on bleeding complications in patients who underwent skin tumor surgery.

TRIAL REGISTRATION

IRCT201602049768N5 Flow chart of the study process and its final finding.

摘要

未标注

我们调查了接受皮肤肿瘤手术患者出血并发症的发生率，并在阿司匹林使用者和安慰剂对照组之间进行了比较。在这项双盲随机对照试验中，比较了32名术前继续服用阿司匹林的患者（干预组）和38名术前停用阿司匹林的患者（安慰剂组）在术中及术后的出血问题、血肿和凝血障碍的局部体征。研究组之间术中出血无统计学显著差异（P = 0.107）。我们得出结论，继续使用阿司匹林治疗对接受皮肤肿瘤手术患者的出血并发症无显著影响。

试验注册

IRCT201602049768N5 研究过程及其最终结果的流程图。