Cozanitis Dimitri A
Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, PO Box 340 (Haartmaninkatu 4), 00029 HUS, Helsinki, Finland.
Wien Med Wochenschr. 2016 Nov;166(15-16):487-499. doi: 10.1007/s10354-016-0481-y.
In 1957, Professor Daniel Bovet received the Nobel Prize in Physiology or Medicine for his studies on various compounds including the muscle relaxants gallamine and succinylcholine that became very useful in anaesthesia. Textbooks credit Professor Bovet for the discovery of these drugs. However, although he indeed did discover their pharmacological character, the actual syntheses were made by Ernest Fourneau and Reid Hunt, respectively; sadly, these two scientists have largely been ignored. In this paper, a brief biography of Bovet is presented along with some of his more notable accomplishments. Particular emphasis has been placed on gallamine and succinylcholine along with their history. In an attempt to undo the "injustice" dealt to both Fourneau and Hunt, brief accounts of their history, story and character are provided.
1957年，丹尼尔·博韦教授因其对包括肌肉松弛剂加拉明和琥珀酰胆碱在内的各种化合物的研究而获得诺贝尔生理学或医学奖，这些化合物在麻醉领域变得非常有用。教科书将这些药物的发现归功于博韦教授。然而，尽管他确实发现了它们的药理特性，但实际的合成分别是由欧内斯特·富尔诺和里德·亨特完成的；遗憾的是，这两位科学家在很大程度上被忽视了。在本文中，介绍了博韦的简要生平以及他的一些更显著的成就。特别强调了加拉明和琥珀酰胆碱以及它们的历史。为了消除对富尔诺和亨特的“不公”，本文简要介绍了他们的经历、故事和性格。
