维持性血液透析患者甲状旁腺切除术后临床变量与死亡率之间的关联。

Association between clinical variables and mortality after parathyroidectomy in maintenance hemodialysis patients.

作者信息

Chen Jin-Bor, Chou Fong-Fu, Yang Cheng-Hong, Hua Moi-Sin

机构信息

Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

Department of Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 123 Ta Pei Road, Niao Song District, Kaohsiung, Taiwan.

出版信息

Am J Surg. 2017 Jan;213(1):140-145. doi: 10.1016/j.amjsurg.2016.03.012. Epub 2016 Jun 14.

DOI:10.1016/j.amjsurg.2016.03.012

PMID:27469221

Abstract

BACKGROUND

We investigated factors associated with all-cause mortality and cardiovascular disease (CVD)-associated mortality after parathyroidectomy (PTX) in patients on maintenance hemodialysis (HD).

METHODS

Our study population consisted of 161 consecutive HD patients who underwent PTX before 2009 and 354 consecutive HD patients without PTX as controls from those visiting the Kaohsiung Chang Gung Memorial Hospital, Taiwan between 2009 and 2013. All-cause and CVD mortality with clinical variables were compared in PTX and non-PTX HD patients.

RESULTS

PTX patients had significantly lower all-cause and CVD mortality than controls. Multivariate logistic regression analyses showed PTX patients had a lower odds ratio for all-cause mortality than those without (odds ratio = .35, 95% confidence interval = .16 to .74). Association analysis based on clinical variables revealed patients with higher hemoglobin, albumin, creatinine, and HD adequacy index-Kt/V levels had significantly decreased risk of all-cause mortality.