Iida K, Sato S, Yui N, Togawa T, Sakata S, Nakano M
Rinsho Hoshasen. 1989 Apr;34(4):481-7.
During 1972-1986, 217 cases of breast cancer patients following radical mastectomy received postoperative radiotherapy and chemotherapy at Chiba Prefectural Cancer Center Hospital. All patients had operable tumor (T1-3), and radiation was directed to the chest wall and regional nodes. A total of 57 patients have relapsed. Fourteen patients experienced isolated local-regional recurrence (11 chest wall, 2 supraclavicular and 1 axilla), and other cases developed distant metastases. Of these, forty patients (70%) died with different metastatic areas within three years, although salvage radiotherapy was effective in controlling the local or metastatic tumor. Of ten patients who survived three years or longer were, six were bone metastaes and four were chest wall recurrence.
1972年至1986年间,217例接受根治性乳房切除术的乳腺癌患者在千叶县癌症中心医院接受了术后放疗和化疗。所有患者的肿瘤均可手术切除(T1-3期),放疗部位为胸壁和区域淋巴结。共有57例患者复发。14例患者出现孤立性局部区域复发(11例为胸壁复发,2例为锁骨上复发,1例为腋窝复发),其他病例发生远处转移。其中,40例患者(70%)在三年内因不同转移部位死亡,尽管挽救性放疗在控制局部或转移性肿瘤方面有效。在存活三年或更长时间的10例患者中,6例发生骨转移,4例为胸壁复发。