Experimental Laboratory of Immunological and Rheumatologic Researches, Istituto Auxologico; private practice in Rome, Italy.
Private practice in Matera, Italy.
J Biol Regul Homeost Agents. 2016 Apr-Jun;30(2 Suppl 1):61-8.
The aim of this case series was to evaluate the clinical outcome of preformed titanium foil (PTF) to perform guided bone regeneration (GBR) in posterior mandibular atrophies. Thirteen patients (4 male; 9 female; mean age 58.85±10.16 years), with class II division C atrophy, according to Misch, were selected to perform GBR by means of PTF, using a moldable allograft paste as graft material. The devices, made of a 0.2mm thick pure titanium foil, were pre-shaped using stereolithographic models obtained from CT-scan of the patients recipient sites. In the second stage, performed at 6.35±2.15 months, 23 cylindrical two-piece implants were placed and the devices removed. At four months, the implants were exposed and submitted to progressive prosthetic load for a span of 4 months. The cases were finalized by means of metal-ceramic cementable restorations. The post finalization follow-up was at 12 months. Survival rate (i.e. SVR) was 100% since no fixtures were lost. At the one-year follow up, the clinical appearance of the soft tissues was optimal and no pathological signs on probing were recorded. The success rate (i.e. SCR) was 82.6% and the average peri-implant bone reabsorption was 0.99±0.59 mm. The results suggest good potentialities of this method for bone volume augmentation in distal mandibular atrophies, allowing to maximize the outcome and simplifying the surgical phase.
本病例系列旨在评估预成型钛箔(PTF)在下颌后萎缩中的引导骨再生(GBR)的临床效果。选择 13 名患者(4 名男性;9 名女性;平均年龄 58.85±10.16 岁),根据 Misch 分类为 II 类 C 型萎缩,使用可塑同种异体糊剂作为移植物材料进行 GBR。该设备由 0.2mm 厚的纯钛箔制成,使用从患者接受部位的 CT 扫描获得的立体光刻模型预先成型。在第 2 阶段,在 6.35±2.15 个月时,放置 23 个圆柱形两件式植入物并去除设备。在第 4 个月,暴露植入物并进行 4 个月的渐进式修复体负荷。通过金属陶瓷可粘结修复体完成病例。最终随访时间为 12 个月。由于没有固定装置丢失,生存率(即 SVR)为 100%。在 1 年的随访中,软组织的临床外观最佳,探诊未记录到任何病理迹象。成功率(即 SCR)为 82.6%,种植体周围骨吸收率平均为 0.99±0.59mm。结果表明,该方法在下颌后萎缩的骨量增加方面具有良好的潜力,允许最大限度地提高效果并简化手术阶段。