Sato M
Nihon Hifuka Gakkai Zasshi. 1989 Jan;99(1):15-23.
The results of patch tests with mercury compounds and disinfectant solutions as well as the clinical picture of mercury contact dermatitis are presented and discussed. During the period from Nov. 1983 to Dec. 1986, 686 patients were tested with mercury compounds. During the 13 year period from 1974-1986, 118 patients were tested with disinfectant solutions and 59 patients with mercury contact dermatitis were seen. Among the disinfectant solutions tested, the highest incidence of positive reaction, 11.5%, was obtained with thimersal. Cross sensitization has been shown between mercurochrome and ammoniated mercury, but no statistical correlation existed that demonstrated cross sensitization between mercury and thimerosal until our study. Therefore, the allergen in mercurochrome contact dermatitis is mercury. No statistical correlation could be established between the occurrence of atopic dermatitis and the patch test reactions to mercury compounds. The contactants were mercurochrome, thimerosal, and broken thermometers in 49 out of 59 cases of mercury contact dermatitis. Consequently, the number of occurrence of mercury dermatitis can be reduced by the elimination of the use of these two disinfectant solutions and the substitution of electric thermometers for mercury thermometers.
本文展示并讨论了汞化合物和消毒剂溶液的斑贴试验结果以及汞接触性皮炎的临床表现。1983年11月至1986年12月期间，686例患者接受了汞化合物检测。在1974年至1986年的13年期间，118例患者接受了消毒剂溶液检测，共观察到59例汞接触性皮炎患者。在所检测的消毒剂溶液中，硫柳汞的阳性反应发生率最高，为11.5%。红汞和白降汞之间已显示出交叉致敏，但在我们的研究之前，没有统计学相关性表明汞和硫柳汞之间存在交叉致敏。因此，红汞接触性皮炎中的变应原是汞。特应性皮炎的发生与汞化合物斑贴试验反应之间无法建立统计学相关性。在59例汞接触性皮炎病例中，有49例的接触物为红汞、硫柳汞和破损的体温计。因此，通过停止使用这两种消毒剂溶液并用电子体温计替代水银体温计，可以减少汞性皮炎的发生数量。
