a Center for Biostatistics in AIDS Research and the Department of Biostatistics , Harvard University , Boston , MA , USA.
b Epidemiology and Public Health , University of Maryland , MD , USA.
Virulence. 2017 May 19;8(4):453-459. doi: 10.1080/21505594.2016.1213473. Epub 2016 Jul 28.
Carbapenem-resistant Enterobacteriaceae (CRE) are an emerging and troublesome group of pathogens. Risk factor studies, outcome studies, and randomized trials are three types of studies conducted to answer different types of questions regarding CRE. These studies pose different types of challenges. We discuss issues in the design and analyses of case-control studies, cohort studies, and randomized trials aimed to address various research questions regarding CRE.
耐碳青霉烯肠杆菌科(CRE)是一组新兴且令人头疼的病原体。风险因素研究、结局研究和随机试验是为回答有关 CRE 的不同类型问题而进行的三种类型的研究。这些研究提出了不同类型的挑战。我们讨论了旨在解决各种有关 CRE 研究问题的病例对照研究、队列研究和随机试验的设计和分析中的问题。